肥胖是肺动脉血栓栓塞的危险因素

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Оксана Ярославна Васильцева, Ирина Николаевна Ворожцова, Ростислав Сергеевич Карпов
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引用次数: 1

摘要

研究的目的。基于2003-2012年托木斯克市医院新发肺栓塞(PE)病例登记册数据,探讨肥胖对静脉血栓栓塞发展的贡献。材料和方法。研究对象是2003-2012年在托木斯克医院接受治疗的患者的病史和尸检记录,这些患者在病理解剖和/或仪器研究中发现肺栓塞。根据世卫组织标准(1997年)对肥胖程度进行了评估。使用PC Statistica 8.0 for Windows软件包对结果进行统计处理。采用Shapiro-Wilk检验和调整后的Lillieforsa的Kolmogorov-Smirnov检验数量性状分布的正态性。使用Fisher精确检验和Cochran检验检验总体方差是否相等。认为p < 0.05有统计学意义。研究的结果。在西西伯利亚,托木斯克,医院肺栓塞登记(2003-2012年)。在登记中包括720例体内和/或死后发现肺栓塞(PE)的患者。分析了医疗记录和尸检报告中的数据发现肺栓塞、内科和外科患者的BMI (p = 0.033)和肥胖(p = 0.002)存在统计学意义上的差异。在内科、外科和血栓栓塞患者中,女性肥胖明显比男性更常见(p = 0.050和p = 0.041分别)。根据这项研究,1级或2级肥胖单独(在患者单独存在的情况下)不会显著增加大块血栓栓塞的几率。然而,3级肥胖使大规模肺栓塞的几率增加了2.7倍以上(OR = 2.708, CI: 1461 - 5020)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ожирение как фактор риска тромбоэмболии легочной артерии
The aim of the study. Based on the data of the Register of new cases of hospital pulmonary embolism (PE) in hospitals in Tomsk (2003–2012), to explore the contribution of obesity to the development of venous thromboembolism. Material and Methods. Study were subjected to medical history and records of autopsies of patients treated in hospitals in Tomsk in 2003–2012, who at patologoanatomic and/or instrumental study revealed pulmonary embolism. The degree of obesity was assessed according to WHO criteria (1997). Statistical processing of the results was carried out using the software package for PC Statistica 8.0 for Windows. To test the normality of the distribution of quantitative traits using the Shapiro–Wilk test and the Kolmogorov–Smirnov with the adjusted Lillieforsa. Check the equality of the population variance was performed using Fisher's exact test and Cochran. Was considered statistically significant level of p < 0.05. The results of the study. In Western Siberia, Tomsk, a register of hospital pulmonary embolism (2003–2012). In the register included 720 patients with in vivo and/or post mortem revealed pulmonary embolism (PE). Analyzed data from medical records and autopsy reports. Revealed statistically significant differences in BMI (p = 0.033) and the presence of obesity (p = 0.002) in patients with pulmonary embolism, holding medical and surgical beds. As of medical, surgical and among patients with thromboembolism, obesity is significantly more common in women than men (p = 0.050 and p = 0.041 respectively). According to the study, obesity grade 1 or 2 alone (at the isolated presence of the patient) is not significantly increased the odds of a massive thromboembolism. However, grade 3 obesity increased the odds of a massive pulmonary embolism by more than 2.7 times (OR = 2.708, CI: 1,461–5,020).
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来源期刊
Byulleten Sibirskoy Meditsiny
Byulleten Sibirskoy Meditsiny MEDICINE, GENERAL & INTERNAL-
CiteScore
0.70
自引率
50.00%
发文量
102
审稿时长
8 weeks
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