格伦手术应尽快完成,并确定在平均肺动脉压升高之前

H. A. Aljadayel, Reza Abbaszadeh, B. Azari, M. Meraji, Gholamreza Azari, Yasaman Khalili, Akbar Nikpajouh
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摘要

关于肺动脉底压对Glenn手术后果的影响,目前的研究结果还存在矛盾,需要进一步的研究。研究目的:我们的主要目的是评估这一假设,即使用Glenn手术技术(Glenn分流器植入)可以通过保持肺动脉压来改善Fontan手术候选单心室心脏患者的预后,而高基线肺动脉压被认为是预后不良的危险因素。方法:本研究对2019年1月1日至2020年3月3日在德黑兰Shahid Rajaei心脏中心连续81例接受孤立格伦手术的单心室心脏缺损患者进行回顾性研究,根据血管造影评估肺动脉压,将患者分为两组。比较A组患者肺动脉压≤15mmhg (n=41)和B组患者肺动脉压≥15mmhg (n= 40)及两组术后预后信息。结果:腹水患病率(3例)。7.4%对19点。B组患者平均住院时间(6.00±2.37天比9.48±6.86天,p = 0.16)和ICU住院时间(3.93±1.07天比5.30±2.30天,p = 0.008)均长于PAP >15 mmHg组(p = 0.192),但两组心律失常发生率无差异(p = 0.192)。结论:肺动脉高压与更多的术后并发症相关,肺动脉高压与术后腹水、胸腔积液及长期住院有关,可被认为是Glenn手术患者的预后因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Glenn procedure should be done as soon as possible and definitely before the mean Pulmonary artery pressure elevated
Introduction : There are still conflicting results regarding the effect of basal pulmonary arterial pressure on the consequences of Glenn surgery and require further studies in this regard. Aim of the study : Our main goal was to assess this hypothesis that the use of Glenn surgical technique (Glenn shunt implantation) can lead to better prognosis in patients with a single ventricular heart who are candidate of Fontan surgery by preserving pulmonary artery pressure, while that high baseline pulmonary artery pressure is considered a risk factor for poor prognosis. Methods: This retrospective study was conducted on 81 consecutive patients with single ventricle heart defect who underwent isolated Glenn surgery and their files were complete in Shahid Rajaei Heart Center in Tehran from 1 January 2019 till 3 March 2020 Based on the pulmonary artery pressure assessed by angiography, patients were classified into two groups, group A patients whose pulmonary artery pressure equal to or less than 15 mmHg (n=41) and group B patients whose pulmonary artery pressure above 15 mmHg (n = 40) and information on the outcome after surgery was compared between the two groups. Results: The prevalence rate of ascites (3 pts. 7.4% versus 19 pts. 48.1%, p = 0.001) and pleural effusion (33.3% versus 85.2%, p = 0.001), the mean length of hospital stay (6.00 ± 2.37 days versus 9.48 ± 6.86 days, p = 0.16) and length of ICU stay (3.93 ± 1.07 days versus 5.30 ± 2.30 days, p = 0.008) all were longer in those patients with PAP >15 mmHg (group B). But there was no difference in the rate of cardiac arrhythmia between the groups (p = 0.192) in our study. Conclusion: High pulmonary artery pressure is associated with more postoperative complications and can be considered as a prognostic factor in patients undergoing Glenn surgery as in fact, high pulmonary pressure associated with postoperative ascites, pleural effusion, and long-term hospitalization.
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