青少年常见脂质紊乱的筛查和治疗。

S. R. Bialo, C. Boney
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引用次数: 0

摘要

心血管疾病仍然是成年人口的一个重大卫生保健负担,其根源始于儿童时期。在所有儿童和青少年中实施了普遍的血脂异常筛查,以确定常规筛查遗漏的FH病例,因为未经治疗的FH可导致早期心血管疾病和过早死亡。药物治疗的建议没有随着2011年NHLBI指南而改变。治疗目标LDL水平通常因原发性遗传疾病(如FH)而升高。尽管这些建议仍然存在争议,但普遍筛查和高危患者后续治疗的益处远远超过不筛查的风险,尽管需要更多的调查来了解青少年心血管疾病风险的长期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Screening and Treatment of Common Lipid Disorders in Adolescents.
Cardiovascular disease remains a substantial health care burden in the adult population, the roots of which begin in childhood. Universal screening for dyslipidemia in all children and adolescents has been implemented to identify cases of FH that are otherwise missed by conventional screening because untreated FH can result in early CVD and untimely death. Recommendations for medical therapy did not change with the 2011 NHLBI guidelines. LDL levels targeted for therapy usually are elevated because of primary genetic disorders such as FH. Although these recommendations remain controversial, the benefit of universal screening and subsequent treatment of high-risk patients far outweighs the risk of not screening, although more investigation is warranted to understand the long-term outcomes of CVD risk in youth.
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来源期刊
Adolescent Medicine: State of the Art Reviews
Adolescent Medicine: State of the Art Reviews Medicine-Pediatrics, Perinatology and Child Health
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