O. Gabriel, Shinshima, Iveren, S. Fatima, Gbadamosi Ismail, Amedu Nathaniel, K. Risikat
{"title":"哺乳期尼古丁改变Wistar大鼠胰腺组织形态学和碳水化合物代谢","authors":"O. Gabriel, Shinshima, Iveren, S. Fatima, Gbadamosi Ismail, Amedu Nathaniel, K. Risikat","doi":"10.15761/brcp.1000187","DOIUrl":null,"url":null,"abstract":"Methods: A total of thirty female rats were used in the experiment; they were grouped into three, Group A served as the control group and received 0.1 ml normal saline in the first 14 days of postnatal life, Groups B and C served as the treated groups and received 0.05 ml of nicotine on the first 7 and 14 days of postnatal life respectively. The rats were weighed before and during gestation; the pups were also weighed while lactating on days 1, 4, 7, 10 and 14 before sacrifice on day 15. Tissue processing was done using Haematoxylin & Eosin and Periodic-Acid Schiff staining methods.","PeriodicalId":92336,"journal":{"name":"Biomedical research and clinical practice","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lactational nicotine alters pancreatic histomorphology and carbohydrate metabolism in Wistar rats\",\"authors\":\"O. Gabriel, Shinshima, Iveren, S. Fatima, Gbadamosi Ismail, Amedu Nathaniel, K. Risikat\",\"doi\":\"10.15761/brcp.1000187\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Methods: A total of thirty female rats were used in the experiment; they were grouped into three, Group A served as the control group and received 0.1 ml normal saline in the first 14 days of postnatal life, Groups B and C served as the treated groups and received 0.05 ml of nicotine on the first 7 and 14 days of postnatal life respectively. The rats were weighed before and during gestation; the pups were also weighed while lactating on days 1, 4, 7, 10 and 14 before sacrifice on day 15. Tissue processing was done using Haematoxylin & Eosin and Periodic-Acid Schiff staining methods.\",\"PeriodicalId\":92336,\"journal\":{\"name\":\"Biomedical research and clinical practice\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedical research and clinical practice\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15761/brcp.1000187\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical research and clinical practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/brcp.1000187","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Lactational nicotine alters pancreatic histomorphology and carbohydrate metabolism in Wistar rats
Methods: A total of thirty female rats were used in the experiment; they were grouped into three, Group A served as the control group and received 0.1 ml normal saline in the first 14 days of postnatal life, Groups B and C served as the treated groups and received 0.05 ml of nicotine on the first 7 and 14 days of postnatal life respectively. The rats were weighed before and during gestation; the pups were also weighed while lactating on days 1, 4, 7, 10 and 14 before sacrifice on day 15. Tissue processing was done using Haematoxylin & Eosin and Periodic-Acid Schiff staining methods.
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