2001-2012年巴西托坎廷斯州15岁以下儿童汉森病:流行病学模式和时间趋势。

Q2 Medicine
Lorena Dias Monteiro, Francisco Rogerlândio Martins Mello, T. P. Miranda, J. Heukelbach
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引用次数: 8

摘要

托坎廷斯是巴西麻风病高流行最严重的州。目的了解2001 - 2012年托坎廷斯地区15岁以下儿童麻风病流行病学特征及相关指标的变化趋势。方法:伤情通报信息系统(SINAN)数据分析。15岁以下的新病例也包括在该州。对指标进行了计算,并通过联结点回归分析了时间趋势。结果患儿1225例,平均年龄10.8岁,以男性为主(52%)。自发需求检测占55.8%,有肢体残疾的占9%以上。2001年至2008年间,< 15年的检出率显著增加(年变化百分比- APC = 3.8%;置信区间为95% - 95% ci 0.1 - 7.6),并在2008 - 2012年间呈现显著下降(APC = -9.4%;95%ci -17.2 - -0.8)。2级病例的检测具有稳定性(APC = 4.2%;95%CI -6.7 - 16.3), 2级病例比例(APC = 4.1%;95%CI 6.7 - 16.3), 1级病例比例(APC = 1.3%;95%CI -6.2 - 9.3),多菌比(APC = 2.9%;95%CI -1.7 - 7.7),少杆菌比例(APC = 2.9%;95%ci -1.7 - 7.7)。结论麻风病仍是托坎廷斯地区重要的公共卫生问题,传播活跃,传播灶持续存在。指标的稳定性表明晚期诊断和被压抑的需求的持久性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hansen's disease in children under 15 years old in the state of Tocantins, Brazil, 2001-2012: epidemiological patterns and temporal trends.
INTRODUCTION Tocantins is the most hyperendemic state for leprosy in Brazil. OBJECTIVE To describe the epidemiological characteristics and temporal trends of leprosy indicators in children under 15 years old in Tocantins between the years of 2001 and 2012. METHODOLOGY Data analysis of the Notification of Injury Information System (SINAN). New cases under the age of 15 have been included in the state. The indicators were calculated and the temporal trends were analyzed through the join-point regression. RESULTS There were 1,225 cases in children, mean age of 10.8 years, and male predominated (52%). The mode of detection by spontaneous demand prevailed (55.8%) and more than 9% had some physical disability. Detection in < 15 years was significantly increased between 2001 and 2008 (anual percent change - APC = 3.8%; confidence interval of 95% - 95%CI 0.1 - 7.6), and showed significant decline between 2008 and 2012 (APC = -9.4%; 95%CI -17.2 - -0.8). There was stability for the detection of grade 2 cases (APC = 4.2%; 95%CI -6.7 - 16.3), proportion of grade 2 cases (APC = 4.1%; 95%CI 6.7 - 16.3), proportion of grade 1 cases (APC = 1.3%; 95%CI -6.2 - 9.3), multibacillary ratio (APC = 2.9%; 95%CI -1.7 - 7.7), and proportion of paucibacillary (APC = 2.9%; 95%CI -1.7 - 7.7). CONCLUSION Leprosy remains an important public health problem in Tocantins, with active transmission and persistence of transmission foci. The stability of the indicators points out the permanence of the late diagnosis and the repressed demands.
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来源期刊
Revista Brasileira de Epidemiologia
Revista Brasileira de Epidemiologia Medicine-Medicine (all)
CiteScore
3.60
自引率
0.00%
发文量
89
审稿时长
21 weeks
期刊介绍: Revista Brasileira de Epidemiologia (Brazilian Journal of Epidemiology) - every four months, journal published by the ABRASCO - aims at publishing not previously published Original Articles, including critical reviews on specific themes, which may contribute to the development of Epidemiology and related Sciences. Revista also publishes articles in the following categories: Debate aimed at discussing different views of the same theme which may be presented as an original article followed by comments from other authors, reproduction of panels and other similar formats; Notes and Information - notes on primary results of research studies.
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