6岁以下患者肾细胞癌:罕见的临床观察

Q3 Medicine
М. А. Рубанский, Анатолий Петрович Казанцев, П. А. Керимов, О. А. Кириллова, Светлана Николаевна Михайлова, А. С. Тёмный, Е. В. Шарапова, М. В. Рубанская
{"title":"6岁以下患者肾细胞癌:罕见的临床观察","authors":"М. А. Рубанский, Анатолий Петрович Казанцев, П. А. Керимов, О. А. Кириллова, Светлана Николаевна Михайлова, А. С. Тёмный, Е. В. Шарапова, М. В. Рубанская","doi":"10.15690/ONCO.V5I4.1971","DOIUrl":null,"url":null,"abstract":"Background . According to the data of the world literature and own data of observations renal cell carcinoma (RCC) in children is a rare pathology. There are mainly localized and locally common forms of the disease, characterized by a good prognosis and rare reccurence. The tactic of the treatment in this group of patients based on radical surgery. If there are distant metastases, adjuvant chemotherapy is performed. The drug of choice in metastatic forms is a tyrosine kinase ingibitor. Description of a Clinical Case . A review of the world literature on the problem of RCC in children and also the clinical observation of RCC in a 6 years old patient, who treated in N.N. Blokhin National Medical Research Center of Oncology (Moscow), are presented. Now the patient is healthy and is under the dynamic observation. Conclusion . The rarity of RCС requires careful examination and observation of patients, morphological and molecular-genetic study of the tumor for features of biology and develop of «adult» cancer in children.","PeriodicalId":37249,"journal":{"name":"Onkopediatria","volume":"5 1","pages":"278-283"},"PeriodicalIF":0.0000,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Почечно-клеточный рак у пациентки в возрасте 6 лет: редкое клиническое наблюдение\",\"authors\":\"М. А. Рубанский, Анатолий Петрович Казанцев, П. А. Керимов, О. А. Кириллова, Светлана Николаевна Михайлова, А. С. Тёмный, Е. В. Шарапова, М. В. Рубанская\",\"doi\":\"10.15690/ONCO.V5I4.1971\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background . According to the data of the world literature and own data of observations renal cell carcinoma (RCC) in children is a rare pathology. There are mainly localized and locally common forms of the disease, characterized by a good prognosis and rare reccurence. The tactic of the treatment in this group of patients based on radical surgery. If there are distant metastases, adjuvant chemotherapy is performed. The drug of choice in metastatic forms is a tyrosine kinase ingibitor. Description of a Clinical Case . A review of the world literature on the problem of RCC in children and also the clinical observation of RCC in a 6 years old patient, who treated in N.N. Blokhin National Medical Research Center of Oncology (Moscow), are presented. Now the patient is healthy and is under the dynamic observation. Conclusion . The rarity of RCС requires careful examination and observation of patients, morphological and molecular-genetic study of the tumor for features of biology and develop of «adult» cancer in children.\",\"PeriodicalId\":37249,\"journal\":{\"name\":\"Onkopediatria\",\"volume\":\"5 1\",\"pages\":\"278-283\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Onkopediatria\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15690/ONCO.V5I4.1971\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Onkopediatria","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15690/ONCO.V5I4.1971","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

背景。根据国际文献资料及本人观察资料,儿童肾细胞癌(RCC)是一种罕见的病理。本病主要有局限性和局部常见形式,特点是预后好,很少复发。这组患者的治疗策略是根治性手术。如果有远处转移,则进行辅助化疗。转移形式的首选药物是酪氨酸激酶激活剂。临床病例描述。本文对世界上关于儿童肾细胞癌的文献进行了综述,并对1例6岁儿童肾细胞癌的临床观察进行了综述,该患者在莫斯科的Blokhin国家肿瘤医学研究中心接受治疗。目前患者身体健康,正在接受动态观察。结论。RCС的罕见性需要对患者进行仔细的检查和观察,对肿瘤的生物学特征和“成人”癌症在儿童中的发展进行形态学和分子遗传学研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Почечно-клеточный рак у пациентки в возрасте 6 лет: редкое клиническое наблюдение
Background . According to the data of the world literature and own data of observations renal cell carcinoma (RCC) in children is a rare pathology. There are mainly localized and locally common forms of the disease, characterized by a good prognosis and rare reccurence. The tactic of the treatment in this group of patients based on radical surgery. If there are distant metastases, adjuvant chemotherapy is performed. The drug of choice in metastatic forms is a tyrosine kinase ingibitor. Description of a Clinical Case . A review of the world literature on the problem of RCC in children and also the clinical observation of RCC in a 6 years old patient, who treated in N.N. Blokhin National Medical Research Center of Oncology (Moscow), are presented. Now the patient is healthy and is under the dynamic observation. Conclusion . The rarity of RCС requires careful examination and observation of patients, morphological and molecular-genetic study of the tumor for features of biology and develop of «adult» cancer in children.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Onkopediatria
Onkopediatria Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.60
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信