脂肪酶催化无溶剂合成聚甘油10 (PG-10)酯

IF 1.6 4区生物学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Chemical and Biochemical Engineering Quarterly Pub Date : 2020-01-01 DOI:10.15255/cabeq.2019.1702

Y. Satyawali, L. Cauwenberghs, W. Dejonghe

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引用次数: 2

摘要

聚甘油脂肪酸酯作为乳化剂广泛应用于食品、医药、化妆品等行业，本研究以无溶剂酶法合成聚甘油脂肪酸酯为研究对象。以前有关于酶法合成各种聚甘油酯的报道;然而，本研究将合成扩展到PG-10酯。考察了底物摩尔比、添加乳化剂增强混合、添加分子筛或N2冲洗除水的影响。采用氮气冲洗法进行无溶剂合成，脂肪酸完全转化，得到完全无酸的产物。该合成方法被验证为聚甘油酯月桂酸酯和聚甘油酯辛酸酯，这两种产品在化妆品工业中都很有用。

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Lipase-catalyzed Solvent-free Synthesis of Polyglycerol 10 (PG-10) Esters

Polyglycerol fatty acid esters, which have been widely used as emulsifiers in food, medicine and cosmetics industries, were the subject of solvent-free enzymatic synthesis in this study. There have been previous reports on enzymatic synthesis of various polyglycerol esters; however, this investigation extends the synthesis to PG-10 esters. The effects of substrate molar ratio, addition of emulsifiers to enhance mixing, and addition of molecular sieves or N2 flushing for water removal, was investigated. The solvent-free synthesis using N2 flushing leads to complete conversion of fatty acid, yielding a completely acid free product. The synthesis is validated for polyglycerol laurate and polyglycerol caprylate, both useful products in the cosmetic industry.

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来源期刊

Chemical and Biochemical Engineering Quarterly 工程技术-工程：化工

CiteScore

2.70

自引率

6.70%

发文量

审稿时长

>12 weeks

期刊介绍： The journal provides an international forum for presentation of original papers, reviews and discussions on the latest developments in chemical and biochemical engineering. The scope of the journal is wide and no limitation except relevance to chemical and biochemical engineering is required. The criteria for the acceptance of papers are originality, quality of work and clarity of style. All papers are subject to reviewing by at least two international experts (blind peer review). The language of the journal is English. Final versions of the manuscripts are subject to metric (SI units and IUPAC recommendations) and English language reviewing. Editor and Editorial board make the final decision about acceptance of a manuscript. Page charges are excluded.