膝关节骨关节炎患者步态过程中疾病进展的定量评估

IF 0.8 Q4 ENGINEERING, BIOMEDICAL
Kiyoshi Tsurumiya, Wataru Hayasaka, Akira Komatsu, Hiroaki Tsukamoto, Tomohiro Suda, T. Iwami, Y. Shimada
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引用次数: 3

摘要

膝骨关节炎(KOA)是一种常见的下肢关节疾病。病情恶化会降低患者的生活质量。内翻突(VT)是KOA患者异常步态之一,被认为是评估KOA的有效指标。因此,一些研究使用不同的测量方法来评估VT。由于VT是瞬间的膝关节侧向运动,增加了膝关节内翻角度和力矩,光学运动捕捉系统得到了广泛的应用。然而,光学动作捕捉系统在临床应用中存在成本高、技术技能要求高、附着过程耗时等缺点。近年来,惯性测量单元(IMU)作为一种测量系统取代了光学运动捕捉系统。基于imu的方法由于其简单性被认为比光学运动捕捉系统更适合于VT评估。本研究旨在利用imu评估KOA患者的步态,并根据疾病进展定量评估VT。为此,我们招募了7名健康参与者和15名KOA患者。随后,他们的膝关节被分为3个进展组:14个健康(0级)膝关节,9个3级膝关节,14个4级膝关节。作为一项步态测试,所有参与者在躯干、大腿和小腿上都佩戴了imu,并走过一条10米长的人行道。VT被认为是中外侧加速度和外翻角速度数据的第一个峰值,这些数据是通过两个小腿的imu收集的。之后,在三个进展组中比较和评估这些获得的数据。结果表明,KOA患者的两个峰值均显著高于健康人群。两个峰值之间存在显著的正相关关系。因此,本研究有望为KOA的早期发现做出贡献。膝关节骨关节炎,生物力学。中国生物医学工程学报,2016,34(1):391 - 391。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quantitative Evaluation Related to Disease Progression in Knee Osteoarthritis Patients During Gait
Knee osteoarthritis (KOA) is a common joint disease of the lower limbs. Its progression reduces the patients ʼ quality of life. Varus thrust (VT), one of the abnormal gait patterns of KOA patients, is considered as an effective index for assessing KOA. Hence, several studies have assessed VT using various measurement methods. Since VT is the momentary lateral knee motion that increases knee varus angle and moment, optical motion capture system is widely used. However, optical motion capture system has some disadvantages in clinical usage, such as high cost, requirement of technical skills, and time-consuming attachment process. Recent-ly, inertial measurement units (IMU) have emerged as a measurement system instead of optical motion capture systems. IMU-based method is regarded as more suitable than optical motion capture systems for VT assessment because of its simplicity. This study aimed to assess the gait of KOA patients using IMUs and to quantitatively evaluate VT based on disease progression. For this purpose, we recruited 7 healthy participants and 15 KOA patients. Subsequently, their knees were classified into 3 progression groups: 14 healthy (grade 0) knees, 9 grade 3 knees, and 14 grade 4 knees. As a gait test, all the participants wore IMUs positioned at the trunk, both thighs, and both shanks, and traversed a 10-m walkway. VT was considered as the first peak value of the mediolateral acceleration and the varus–valgus angular velocity data, which were collected via the IMUs at both shanks. Thereafter, these acquired data were compared and evaluated among the three progression groups. The results indicate that both peak values were significantly greater in the KOA patients than in the healthy subjects. Moreover, there was a significant positive correlation between the two peak values. Thus, this study is ex-pected to contribute toward early detection of KOA. knee osteoarthritis, biomechanics. Adv Biomed Eng. 10 : pp. 51–57, 2021.
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来源期刊
Advanced Biomedical Engineering
Advanced Biomedical Engineering ENGINEERING, BIOMEDICAL-
CiteScore
1.40
自引率
10.00%
发文量
15
审稿时长
15 weeks
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