不丹干牦牛奶酪乳酸菌对小鼠巨噬细胞细胞因子基因表达的刺激作用

Bioscience and microflora Pub Date : 2005-10-01 DOI:10.12938/BIFIDUS.24.125

Y. Ohashi, K. Nagai, M. Tokunaga, K. Ushida, Tomomi Yamada

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引用次数: 0

摘要

研究了从不丹喜马拉雅地区牦牛干奶酪中分离的乳酸菌(LAB)刺激小鼠巨噬细胞细胞因子mRNA表达的能力。几种菌株均能刺激肿瘤坏死因子-a、白细胞介素(IL) 6或IL- 12p40基因的表达。Chugo干牦牛奶酪含有具有免疫调节作用的乳酸菌。

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Stimulation of Cytokine Gene Expression in a Murine Macrophage Cell Line by Lactic Acid Bacteria Isolated from Bhutanese Dried Yak Cheese

Lactic acid bacteria (LAB) isolated from dried yak cheese from the Bhutan Himalayas were examined for their ability to stimulate the expression of cytokine mRNA on the murine macrophage. The expression of tumor necrosis factor-a, interleukin (IL) 6 or IL-12 p40 gene was stimulated by several strains. The dried yak cheese, Chugo, contains LAB that possess immuno-modulating activity.

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Bioscience and microflora

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