Yinyi Sun, Kangyong Liu, Ting Zhang, Yan Sun, Wenqi Chen, Qian Li, Rongfu Chen, Xiao-Jiang Sun
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The Neuroprotective Effect and Probable Mechanism of DL-3-n-Butylphthalide in Brain Diseases
3-n-Butylphthalide (NBP), one of the chemical constituents of celery oil, is used for the treatment of many central nervous system diseases, including Parkinson's disease, Alzheimer's disease and cerebral ischemia. NBP showed potent neuroprotective effects by decreasing oxidative damage, inhibiting inflammatory responses, improving mitochondrial function, and reducing neuronal apoptosis.
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