经颅电刺激对大鼠坐骨神经损伤功能恢复影响的电生理研究

Primary sensory neuron : the international interdisciplinary journal reporting basic and clinical research on sensory receptors and primary afferent neurons Pub Date : 1997-01-01 DOI:10.1163/092996397750131964

V. Lebedev, A. Moisseeva, G. Akoev, L. Kolosova, O. V. Riabchikova

{"title":"经颅电刺激对大鼠坐骨神经损伤功能恢复影响的电生理研究","authors":"V. Lebedev, A. Moisseeva, G. Akoev, L. Kolosova, O. V. Riabchikova","doi":"10.1163/092996397750131964","DOIUrl":null,"url":null,"abstract":"The effect of transcranial electrical stimulation at analgesic regimen on regeneration of the rat sciatic nerve after transection and microsurgical suture was studied. Electroanalgesia was found to promote the regenerative outgrowth of the injured nerve fibers, that was manifested in acceleration of foot reinnervation with efferent and afferent nerve fibers by an average of 30 and 25%, respectively. Moreover, electrical stimulation was favorable for the better recovery of the functional properties of the damaged afferents at 9 months after surgery. The involvement of endogenous opioid peptides in regeneration of the peripheral nerves is discussed.","PeriodicalId":82360,"journal":{"name":"Primary sensory neuron : the international interdisciplinary journal reporting basic and clinical research on sensory receptors and primary afferent neurons","volume":"2 1","pages":"177-183"},"PeriodicalIF":0.0000,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1163/092996397750131964","citationCount":"1","resultStr":"{\"title\":\"Electrophysiological study of the effect of transcranial electrical stimulation on the functional recovery of the damaged sciatic nerve in the rat\",\"authors\":\"V. Lebedev, A. Moisseeva, G. Akoev, L. Kolosova, O. V. Riabchikova\",\"doi\":\"10.1163/092996397750131964\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The effect of transcranial electrical stimulation at analgesic regimen on regeneration of the rat sciatic nerve after transection and microsurgical suture was studied. Electroanalgesia was found to promote the regenerative outgrowth of the injured nerve fibers, that was manifested in acceleration of foot reinnervation with efferent and afferent nerve fibers by an average of 30 and 25%, respectively. Moreover, electrical stimulation was favorable for the better recovery of the functional properties of the damaged afferents at 9 months after surgery. The involvement of endogenous opioid peptides in regeneration of the peripheral nerves is discussed.\",\"PeriodicalId\":82360,\"journal\":{\"name\":\"Primary sensory neuron : the international interdisciplinary journal reporting basic and clinical research on sensory receptors and primary afferent neurons\",\"volume\":\"2 1\",\"pages\":\"177-183\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1997-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1163/092996397750131964\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Primary sensory neuron : the international interdisciplinary journal reporting basic and clinical research on sensory receptors and primary afferent neurons\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1163/092996397750131964\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Primary sensory neuron : the international interdisciplinary journal reporting basic and clinical research on sensory receptors and primary afferent neurons","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1163/092996397750131964","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

摘要

研究了镇痛方案下经颅电刺激对大鼠坐骨神经横断及显微外科缝合后再生的影响。电镇痛可促进损伤神经纤维的再生生长，表现为足部传出和传入神经纤维的再神经支配平均分别加速30%和25%。此外，电刺激有利于术后9个月损伤传入神经功能特性的较好恢复。讨论了内源性阿片肽在周围神经再生中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Electrophysiological study of the effect of transcranial electrical stimulation on the functional recovery of the damaged sciatic nerve in the rat

The effect of transcranial electrical stimulation at analgesic regimen on regeneration of the rat sciatic nerve after transection and microsurgical suture was studied. Electroanalgesia was found to promote the regenerative outgrowth of the injured nerve fibers, that was manifested in acceleration of foot reinnervation with efferent and afferent nerve fibers by an average of 30 and 25%, respectively. Moreover, electrical stimulation was favorable for the better recovery of the functional properties of the damaged afferents at 9 months after surgery. The involvement of endogenous opioid peptides in regeneration of the peripheral nerves is discussed.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Primary sensory neuron : the international interdisciplinary journal reporting basic and clinical research on sensory receptors and primary afferent neurons

自引率

0.00%

发文量