利多卡因加芬太尼对经直肠超声引导前列腺活检患者尾侧阻滞的有效浓度

Q2 Medicine

Pain Research and Treatment Pub Date : 2016-10-30 DOI:10.1155/2016/5862931

Jinguo Wang, Honglan Zhou, W. An, Na Wang, Yang Gao

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引用次数: 5

摘要

目标。本研究确定了利多卡因加75 μg芬太尼用于经直肠超声(TRUS)引导前列腺活检患者尾侧阻滞的有效浓度(EC)。方法。连续的男性患者计划在TRUS引导下进行前列腺活检。尾侧阻滞混合溶液含利多卡因和芬太尼75 μg，共20 mL。采用上下法测定利多卡因浓度，从0.8%开始(步长为0.1%)。一个成功的尾侧阻滞被定义为在活检期间没有痛觉。计算利多卡因尾侧阻滞成功后的EC50，并对副作用进行评价。结果。总共招募了23名患者。利多卡因对尾侧阻滞成功的EC50为0.53%。结论。0.53%的利多卡因联合75 μg芬太尼，50%的男性患者行经直肠超声引导下的前列腺活检获得了良好的尾部阻滞。

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Effective Concentration of Lidocaine Plus Fentanyl for Caudal Block in Patients Undergoing Transrectal Ultrasound Guided Prostate Biopsy

Objective. This study determined the effective concentration (EC) of lidocaine plus 75 μg fentanyl for caudal block in patients undergoing transrectal ultrasound (TRUS) guided prostate biopsy. Methods. Consecutive male patients scheduled for TRUS guided prostate biopsy were enrolled. The mixed solution for caudal block contained lidocaine and 75 μg fentanyl, in total 20 mL. The concentration of lidocaine was determined using the up-and-down method, starting at 0.8% (a step size of 0.1%). A successful caudal block was defined by no pain perception during biopsy. The EC50 of lidocaine for successful caudal block was calculated and side effects were evaluated. Results. A total of 23 patients were recruited. The EC50 of lidocaine for successful caudal block was 0.53%. Conclusions. Lidocaine of 0.53% combined with 75 μg fentanyl resulted in excellent caudal block in 50% of male patients undergoing transrectal ultrasound guided prostate biopsy.

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来源期刊

Pain Research and Treatment Medicine-Anesthesiology and Pain Medicine

CiteScore

3.60

自引率

0.00%

发文量