17β-雌二醇对24周去卵巢雌性小鼠皮肤伤口愈合的影响

Journal of hormones Pub Date : 2014-01-21 DOI:10.1155/2014/234632

Kanae Mukai, Yukari Nakajima, T. Urai, Emi Komatsu, Kana Takata, Yuriko Miyasaka, Nasruddin, J. Sugama, T. Nakatani

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引用次数: 8

摘要

雌激素替代促进皮肤伤口愈合8 - 10周的年轻卵巢切除雌性小鼠。然而，据我们所知，使用切除卵巢的老年雌性小鼠进行研究还没有报道。因此，我们研究了17β-雌二醇对24周中年去卵巢雌性小鼠皮肤伤口愈合的影响。将20周龄雌性小鼠分为三组:卵巢切除术后给予17β-雌二醇

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The Effect of 17β-Estradiol Administration on Cutaneous Wound Healing in 24-Week Ovariectomized Female Mice

Estrogen replacement promotes cutaneous wound healing in 8–10-week young ovariectomized female mice. However, research using aged ovariectomized female mice has not been reported, to the best of our knowledge. Therefore, we investigated the effect of 17β-estradiol on cutaneous wound healing using 24-week middle-aged ovariectomized female mice. Twenty-week-old female mice were divided into three groups: medication with 17β-estradiol after ovariectomy (OVX

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Journal of hormones

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