Gadaba的遗传研究:印度安得拉邦的一个部落人口。

IF 0.4 4区 社会学 Q3 ANTHROPOLOGY
Rao Pm, Kirk Rl, Busi Br, Raman Gv, Reddi Gg
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引用次数: 1

摘要

血液样本采集自印度南部安得拉邦的部落人口Gadaba,以检查血型分布、红细胞酶和γ球蛋白多态性。在所研究的20个遗传标记中,有7个蛋白位点表现出单态性。令人惊讶的是,在磷酸葡萄糖酸脱氢酶位点(6-PGD)上观察到1例罕见的纯合变异和21例杂合变异,在磷酸己糖异构酶位点(PHI)上观察到6例变异,在磷酸葡萄糖化酶位点1 (PGM 1)上观察到1例变异。此外,南印度的部落人口比种姓人口显示出更高的罕见变异频率。然而,由于它们的高选择性价值,存在一些表型中性的罕见变异可能是合理的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Genetic studies on Gadaba: a tribal population of Andhra Pradesh, India.
Blood samples were collected from Gadaba, a tribal population of Andhra Pradesh, South India, in order to examine the distribution of blood groups, red cell enzymes and the gammaglobulin polymorphism. Out of 20 genetic markers studied seven protein loci exhibited monomorphism. Surprisingly a case of a rare homozygous variant and twenty-one heterozygous variants at the phosphogluconate dehydrogenase locus (6-PGD), six variants at the phosphohexose isomerase locus (PHI) and a single case of phosphoglucomutase locus 1 (PGM 1) variant were observed. Further, the tribal populations of South India reveal higher frequencies of rare variants than the caste populations. However, the presence of rare variants that are phenotypically neutral may be plausibly due to their high selective value.
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
34
期刊介绍: AA is an international journal of human biology. It publishes original research papers on all fields of human biological research, that is, on all aspects, theoretical and practical of studies of human variability, including application of molecular methods and their tangents to cultural and social anthropology. Other than research papers, AA invites the submission of case studies, reviews, technical notes and short reports. AA is available online, papers must be submitted online to ensure rapid review and publication.
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