{"title":"一种新的“寄生”:线粒体基因组高血压","authors":"D. Holzman","doi":"10.1128/MICROBE.11.338.1","DOIUrl":null,"url":null,"abstract":"Mothers with a specific mutation in a mitochondrial transfer RNA (tRNA) gene may pass a predisposition to high blood pressure on to their children, according to Min-Xin Guan of Zhejiang University, Hangzhou, China, and his collaborators. The observation that hypertension within the three families studied appeared to be inherited exclusively maternally led them to suspect mitochondrial involvement, he says. Details appear in the July 2016 Molecular and Cellular Biology (doi:10.1128/MCB.00199–16).","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.338.1","citationCount":"0","resultStr":"{\"title\":\"A New “Parasitism”: Mitochondrial Genome-Based Hypertension\",\"authors\":\"D. Holzman\",\"doi\":\"10.1128/MICROBE.11.338.1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Mothers with a specific mutation in a mitochondrial transfer RNA (tRNA) gene may pass a predisposition to high blood pressure on to their children, according to Min-Xin Guan of Zhejiang University, Hangzhou, China, and his collaborators. The observation that hypertension within the three families studied appeared to be inherited exclusively maternally led them to suspect mitochondrial involvement, he says. Details appear in the July 2016 Molecular and Cellular Biology (doi:10.1128/MCB.00199–16).\",\"PeriodicalId\":87479,\"journal\":{\"name\":\"Microbe (Washington, D.C.)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1128/MICROBE.11.338.1\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microbe (Washington, D.C.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1128/MICROBE.11.338.1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbe (Washington, D.C.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1128/MICROBE.11.338.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
中国杭州浙江大学的管民新和他的合作者称,线粒体转移RNA (tRNA)基因发生特定突变的母亲可能会将患高血压的倾向遗传给她们的孩子。他说,观察到高血压在三个被研究的家庭中似乎完全是由母亲遗传的,这使他们怀疑线粒体的参与。详情请见2016年7月的Molecular and Cellular Biology (doi:10.1128/ MCB.00199-16)。
A New “Parasitism”: Mitochondrial Genome-Based Hypertension
Mothers with a specific mutation in a mitochondrial transfer RNA (tRNA) gene may pass a predisposition to high blood pressure on to their children, according to Min-Xin Guan of Zhejiang University, Hangzhou, China, and his collaborators. The observation that hypertension within the three families studied appeared to be inherited exclusively maternally led them to suspect mitochondrial involvement, he says. Details appear in the July 2016 Molecular and Cellular Biology (doi:10.1128/MCB.00199–16).