无症状SARS-CoV-2感染的特异性体液免疫特征

Yingying Deng, Jiaxin Zheng, Yong Lin, A. Huang
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摘要

2019年12月爆发的严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)感染给全球公共卫生和全球经济造成了巨大打击。在2019冠状病毒病(COVID-19)流行初期,忽视了SARS-CoV-2感染的无症状个体,没有进行适当的识别和隔离。然而,事实证明,在所有sars - cov -2感染者中,无症状个体占很大比例,这在很大程度上促成了该疾病的快速和广泛传播。本文就SARS-CoV-2的流行病学特征、诊断评估方法、建立无症状感染的相关因素以及无症状个体感染或接种后的体液免疫特征等方面的最新进展进行综述,以期有助于有效控制COVID-19的持续流行。©2023美国临床肿瘤学会。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Characterization of Specific Humoral Immunity in Asymptomatic SARS-CoV-2 Infection
The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in December 2019 caused a huge blow to both global public health and global economy. At the early stage of the coronavirus disease 2019 (COVID-19) epidemic, asymptomatic individuals with SARS-CoV-2 infection were ignored, without appropriate identification and isolation. However, asymptomatic individuals proved to comprise a high proportion of all SARS-CoV-2-infected individuals, which greatly contributed to the rapid and wide spread of this disease. In this review, we summarize the latest advances in epidemiological characteristics, diagnostic assessment methods, factors related to the establishment of SARS-CoV-2 asymptomatic infection, as well as humoral immune features after SARS-CoV-2 infection or vaccination in asymptomatic individuals, which would contribute to effective control of ongoing COVID-19 epidemic. © 2023 American Society of Clinical Oncology.
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