Elevation of biosynthesis of endogenous 17‐B oestradiol by boron supplementation: One possible role of dietary boron consumption in humans

Background. Recent evidence indicates that boron has a widespread role in biochemistry and nutrition and may have anti‐carcinogenic properties. It interacts with calcium, vitamin D and magnesium, which are all important in bone metabolism. Boron also increases steroid hormone concentrations in animals and humans and hints at a role in the prevention of chronic diseases such as osteoporosis, arthritis and other steroid hormone dependent diseases. It has been suggested that the interaction between boron and steroid hormone metabolism is mediated by the hydroxylation process that steroids need to be biologically active. Thus, the aim of this study was to investigate the effect of boron supplementation on the selected steroid hormone productions or steroidogenesis.Methods. The experimental design consisted of two trials, in two different occasions. Seven healthy male volunteers in one group and another nine healthy male volunteers in the second group consumed two tablets each containing 5 mg of boron per day ...