Sen LIU , Nan YANG , Zhao-hua HOU , Yang YAO , Li LÜ , Xian-rong ZHOU , Gui-xing REN
{"title":"燕麦avenanthrides对人血清的抗氧化作用","authors":"Sen LIU , Nan YANG , Zhao-hua HOU , Yang YAO , Li LÜ , Xian-rong ZHOU , Gui-xing REN","doi":"10.1016/S1671-2927(11)60122-3","DOIUrl":null,"url":null,"abstract":"<div><p>The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study. Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon. Plasma lipid peroxides and antioxidant status were measured. For 8 capsules (containing 3.12 mg avenanthramides) groups, the levels of serum Superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantly increased by 8.4 and 17.9%, respectively (P<0.05), and malondialdehyde (MDA) level significantly decreased by 28.1%. The total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1, 28.1, and 15.1%, respectively (P<0.05). The high density blood lipoprotein cholesterol (HDL-C) levels in the same treat was increased by 13.2%. Based on our research, it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans. It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy.</p></div>","PeriodicalId":7475,"journal":{"name":"Agricultural Sciences in China","volume":"10 8","pages":"Pages 1301-1305"},"PeriodicalIF":0.0000,"publicationDate":"2011-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1671-2927(11)60122-3","citationCount":"30","resultStr":"{\"title\":\"Antioxidant Effects of Oats Avenanthramides on Human Serum\",\"authors\":\"Sen LIU , Nan YANG , Zhao-hua HOU , Yang YAO , Li LÜ , Xian-rong ZHOU , Gui-xing REN\",\"doi\":\"10.1016/S1671-2927(11)60122-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study. Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon. Plasma lipid peroxides and antioxidant status were measured. For 8 capsules (containing 3.12 mg avenanthramides) groups, the levels of serum Superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantly increased by 8.4 and 17.9%, respectively (P<0.05), and malondialdehyde (MDA) level significantly decreased by 28.1%. The total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1, 28.1, and 15.1%, respectively (P<0.05). The high density blood lipoprotein cholesterol (HDL-C) levels in the same treat was increased by 13.2%. Based on our research, it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans. It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy.</p></div>\",\"PeriodicalId\":7475,\"journal\":{\"name\":\"Agricultural Sciences in China\",\"volume\":\"10 8\",\"pages\":\"Pages 1301-1305\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S1671-2927(11)60122-3\",\"citationCount\":\"30\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Agricultural Sciences in China\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1671292711601223\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Agricultural Sciences in China","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1671292711601223","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Antioxidant Effects of Oats Avenanthramides on Human Serum
The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study. Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon. Plasma lipid peroxides and antioxidant status were measured. For 8 capsules (containing 3.12 mg avenanthramides) groups, the levels of serum Superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantly increased by 8.4 and 17.9%, respectively (P<0.05), and malondialdehyde (MDA) level significantly decreased by 28.1%. The total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1, 28.1, and 15.1%, respectively (P<0.05). The high density blood lipoprotein cholesterol (HDL-C) levels in the same treat was increased by 13.2%. Based on our research, it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans. It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy.
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