有机合成中的树突载体

Robertus J.M. Klein Gebbink , Cornelis A. Kruithof , Gerard P.M. van Klink, Gerard Van Koten
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引用次数: 29

摘要

概述了树突载体在有机合成中应用的最新进展。介绍了枝状支架在液相和固相有机合成中的应用实例。在液相合成中,可溶性树状大分子被用作底物支撑,而在固相合成中,“树状”不溶性树脂被用于此目的。本文讨论了通过组合技术在树枝状支架上合成化合物文库的实例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dendritic supports in organic synthesis

An overview is presented of the recent developments in the use of dendritic supports in organic synthesis. Examples are presented of the application of dendritic supports in both liquid- and solid-phase organic synthesis. In liquid-phase synthesis, soluble dendrimers are used as the substrate support, while in solid-phase synthesis, ‘dendronized’ insoluble resins are used for this purpose. Selected examples of the synthesis of compound libraries on dendritic supports via combinatorial techniques are discussed.

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