与乙醇溶液相比,精油漱口水对近端菌斑还原和炎症的影响

E. Marchetti , S. Mummolo , G. Marzo , A. Civisca , C. Di Pietro , G. Marinelli
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引用次数: 4

摘要

目的:评估一种漱口水的有效作用是由于其作为有效成分的精油含量还是由于其作为溶剂的高浓度乙醇。材料与方法本试验为随机、对照、平行临床试验,为期四周。28名受试者被平均分为两组,每组14名受试者。第一组给的是漱口水(李斯德林),而第二组给的是含有21.3%乙醇的水酒精溶液。所有患者都被要求每天漱口两次,持续四周。使用近似斑块指数(API)和乳头状出血指数(PBI)评估卫生和近端间炎症水平,测量时间为10、14和28。结果第一组患者api、PBI指数下降,差异有统计学意义;相反,对照组的变化可以忽略不计。结论本临床试验的结果表明,所检查的漱口水的作用不是由于其高浓度的乙醇,而是由于其所含的精油。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effetto di un collutorio agli oli essenziali nella riduzione di placca e infiammazione interprossimali rispetto a una soluzione a base di etanolo

Objectives

To assess whether the well-documented action of a mouthrinse is due either to its content in essential oils as active ingredients or to its high concentration of ethanol as a solvent.

Materials and methods

This randomized, controlled, parallel clinical trial lasted four weeks. Twenty-eight subjects were enrolled and equally divided into two groups of 14 subjects each. The first group was given a mouthrinse (Listerine), whereas the second group was given a hydroalcoholic solution containing 21.3% ethanol. All patients were instructed to rinse their mouth twice a day for four weeks. The approximal plaque index (API) and the papillary bleeding index (PBI) were used to assess hygiene and interproximal inflammation levels, which were measured at t0, t14 e t28.

Results

API and PBI indexes showed a statistically significant decrease in the first group; on the contrary, there were negligible variations in the control group.

Conclusions

The results of this clinical trial suggest that the action of the examined mouthrinse is not due to its high concentration of ethanol, but to its contents in essential oils.

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