{"title":"巨静脉移植动脉瘤并发Loeys-Dietz综合征","authors":"Sosei Kuma MD, PhD , Masaru Ishida MD, PhD , Jin Okazaki MD, PhD , Yoshio Arai MD, PhD , Michiya Hanyu MD, PhD , Katsumi Inoue MD, PhD","doi":"10.1016/j.jvsc.2015.03.015","DOIUrl":null,"url":null,"abstract":"<div><p>Loeys-Dietz syndrome (LDS) is a recently reported autosomal dominant aortic aneurysm syndrome with widespread systemic involvement. Although connective tissue diseases carry a theoretical risk of aneurysmal degeneration in vein grafts, there are no reports of vein graft aneurysm (VGA) in patients with connective tissue disease. We herein report the first case of a giant VGA that was manifested 5 years after the reconstruction of a popliteal artery aneurysm associated with LDS. A pathologic examination of the VGA revealed high proteoglycan deposition and medial degeneration of the diffuse type in the VGA; these findings conformed to LDS.</p></div>","PeriodicalId":91348,"journal":{"name":"Journal of vascular surgery cases","volume":"1 2","pages":"Pages 123-126"},"PeriodicalIF":0.0000,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jvsc.2015.03.015","citationCount":"1","resultStr":"{\"title\":\"Giant vein graft aneurysm complicated by Loeys-Dietz syndrome\",\"authors\":\"Sosei Kuma MD, PhD , Masaru Ishida MD, PhD , Jin Okazaki MD, PhD , Yoshio Arai MD, PhD , Michiya Hanyu MD, PhD , Katsumi Inoue MD, PhD\",\"doi\":\"10.1016/j.jvsc.2015.03.015\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Loeys-Dietz syndrome (LDS) is a recently reported autosomal dominant aortic aneurysm syndrome with widespread systemic involvement. Although connective tissue diseases carry a theoretical risk of aneurysmal degeneration in vein grafts, there are no reports of vein graft aneurysm (VGA) in patients with connective tissue disease. We herein report the first case of a giant VGA that was manifested 5 years after the reconstruction of a popliteal artery aneurysm associated with LDS. A pathologic examination of the VGA revealed high proteoglycan deposition and medial degeneration of the diffuse type in the VGA; these findings conformed to LDS.</p></div>\",\"PeriodicalId\":91348,\"journal\":{\"name\":\"Journal of vascular surgery cases\",\"volume\":\"1 2\",\"pages\":\"Pages 123-126\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.jvsc.2015.03.015\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of vascular surgery cases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352667X15000478\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of vascular surgery cases","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352667X15000478","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Giant vein graft aneurysm complicated by Loeys-Dietz syndrome
Loeys-Dietz syndrome (LDS) is a recently reported autosomal dominant aortic aneurysm syndrome with widespread systemic involvement. Although connective tissue diseases carry a theoretical risk of aneurysmal degeneration in vein grafts, there are no reports of vein graft aneurysm (VGA) in patients with connective tissue disease. We herein report the first case of a giant VGA that was manifested 5 years after the reconstruction of a popliteal artery aneurysm associated with LDS. A pathologic examination of the VGA revealed high proteoglycan deposition and medial degeneration of the diffuse type in the VGA; these findings conformed to LDS.