Luis F. García , Anton Aluja , Oscar García , Lara Cuevas
{"title":"祖克曼心理生物学人格模型框架下的遗传关联研究","authors":"Luis F. García , Anton Aluja , Oscar García , Lara Cuevas","doi":"10.1016/j.anpsic.2016.06.003","DOIUrl":null,"url":null,"abstract":"<div><p>Following Zuckerman's psychobiological personality model, a series of genetic association hypotheses between some polymorphisms of Serotonin, Testosterone, Dopamine, MAO-A and COMT, and three temperamental traits (Impulsive Unsocialized Sensation Seeking, Neuroticism, and Extroversion-Sociability) were tested. In order to surpass previous limitations of this kind of studies: 1) the measurement of the phenotype was improved by using eight personality scales, and 2) some statistical analyses were conducted to test conjointly the effects of the considered polymorphisms. 252 participants from two samples (147 male inmates, and 105 male healthy volunteers) were analyzed. A tendency in the theoretical expected direction is reported when several polymorphisms are considered conjointly. The discussion section recommends applying more integrative frameworks to explore the complex paths from genetics to behavior.</p></div>","PeriodicalId":44066,"journal":{"name":"Anuario de Psicologia","volume":"46 1","pages":"Pages 17-30"},"PeriodicalIF":0.6000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.anpsic.2016.06.003","citationCount":"2","resultStr":"{\"title\":\"Genetic association study within the framework of Zuckerman's psychobiological personality model\",\"authors\":\"Luis F. García , Anton Aluja , Oscar García , Lara Cuevas\",\"doi\":\"10.1016/j.anpsic.2016.06.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Following Zuckerman's psychobiological personality model, a series of genetic association hypotheses between some polymorphisms of Serotonin, Testosterone, Dopamine, MAO-A and COMT, and three temperamental traits (Impulsive Unsocialized Sensation Seeking, Neuroticism, and Extroversion-Sociability) were tested. In order to surpass previous limitations of this kind of studies: 1) the measurement of the phenotype was improved by using eight personality scales, and 2) some statistical analyses were conducted to test conjointly the effects of the considered polymorphisms. 252 participants from two samples (147 male inmates, and 105 male healthy volunteers) were analyzed. A tendency in the theoretical expected direction is reported when several polymorphisms are considered conjointly. The discussion section recommends applying more integrative frameworks to explore the complex paths from genetics to behavior.</p></div>\",\"PeriodicalId\":44066,\"journal\":{\"name\":\"Anuario de Psicologia\",\"volume\":\"46 1\",\"pages\":\"Pages 17-30\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2016-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.anpsic.2016.06.003\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anuario de Psicologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0066512616300034\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PSYCHOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anuario de Psicologia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0066512616300034","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PSYCHOLOGY","Score":null,"Total":0}
Genetic association study within the framework of Zuckerman's psychobiological personality model
Following Zuckerman's psychobiological personality model, a series of genetic association hypotheses between some polymorphisms of Serotonin, Testosterone, Dopamine, MAO-A and COMT, and three temperamental traits (Impulsive Unsocialized Sensation Seeking, Neuroticism, and Extroversion-Sociability) were tested. In order to surpass previous limitations of this kind of studies: 1) the measurement of the phenotype was improved by using eight personality scales, and 2) some statistical analyses were conducted to test conjointly the effects of the considered polymorphisms. 252 participants from two samples (147 male inmates, and 105 male healthy volunteers) were analyzed. A tendency in the theoretical expected direction is reported when several polymorphisms are considered conjointly. The discussion section recommends applying more integrative frameworks to explore the complex paths from genetics to behavior.
期刊介绍：
The Anuario de Psicología, one of Spain"s most important general psychology journals, is published by the Faculty of Psychology of the University of Barcelona. It appears three times a year. The Anuario combines continuity with the past with a strong commitment to the present and the future. The journal is broad-ranging, interdisciplinary, and innovative. The Anuario publishes research reports and applied studies in all fields of psychology. We also accept theorical, epistemological studies, organize dossiers on topical themes, and hold debates on controversial subjects deriving from a central article.
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