谷胱甘肽S-转移酶P1中rs1695与牙周炎风险的遗传相关性：一项初步研究。

IF 1.5 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Biology Research Communications Pub Date : 2023-01-01 DOI:10.22099/mbrc.2023.46999.1815

Rakshitha Vettri Saravanan, Anitha Pandi, Karthikeyan Murthykumar, Smiline Girija Aseervatham Selvi, Paramasivam Arumugam, Vijayashree Priyadharsini Jayaseelan

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引用次数: 0

摘要

本研究旨在确定GSTP1（rs1695）基因多态性与牙周炎风险之间的关系。这项研究采用了横断面设计，包括来自南印度人口的受试者。泰米尔纳德邦Saveetha牙科学院和医院共有100名患者参与了这项研究。根据临床检查，参与者被分为对照组（n=50）和牙周炎组（n=5 0）。采集血样。使用跨越多态位点的特异性引物进行基因分型。rs1695多态性的基因型频率在病例和对照组之间没有显著差异。

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Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study.

The present study aims to determine the association between a genetic polymorphism of GSTP1 (rs1695) and the risk of periodontitis. This study used a cross-sectional design and included subjects from the South Indian population. A total of 100 individuals enrolled at Saveetha Dental College and Hospital, Tamil Nadu were included in this study. The participants were divided into control (n=50) and periodontitis (n=50) based on clinical examination. Blood samples were collected. Genotyping was performed using specific primers spanning the polymorphic site. The genotypic frequencies for the rs1695 polymorphism were not significantly different between cases and controls.

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来源期刊

Molecular Biology Research Communications BIOCHEMISTRY & MOLECULAR BIOLOGY-

CiteScore

3.00

自引率

0.00%

发文量

期刊介绍： “Molecular Biology Research Communications” (MBRC) is an international journal of Molecular Biology. It is published quarterly by Shiraz University (Iran). The MBRC is a fully peer-reviewed journal. The journal welcomes submission of Original articles, Short communications, Invited review articles, and Letters to the Editor which meets the general criteria of significance and scientific excellence in all fields of “Molecular Biology”.