双氧水喷雾器在急救救护车和医院候诊室病毒消毒中的应用

IF 4.1 2区农林科学 Q2 ENVIRONMENTAL SCIENCES

Food and Environmental Virology Pub Date : 2022-03-20 DOI:10.1007/s12560-022-09519-y

Marie Estienney, Philippe Daval-Frerot, Ludwig-Serge Aho-Glélé, Lionel Piroth, Pascal Stabile, Jean-Yves Gerbet, Romain Rouleau, Alexis de Rougemont, Gaël Belliot

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引用次数: 1

摘要

医院设施和救护车的消毒是切断病毒病原体传播链的一个重要问题。过氧化氢在实验室分析中提供了有希望的结果。在这里，我们评估了过氧化氢雾化器在病人候诊室和医疗救护车的设备齐全的机舱中对替代MS2噬菌体和小鼠诺如病毒(MNV)灭活的功效。我们观察到，在这两种情况下，滴度平均降低了3 log10，这意味着每平方厘米分别破坏了超过106个和109个MNV和MS2的感染性颗粒。卫生工作者在对密闭和杂乱的空间进行消毒时，接触病毒的可能性很高，因此使用过氧化氢雾可能是一种经济有效的解决方案，可最大限度地减少病毒污染的风险。

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Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room

Disinfection of hospital facilities and ambulances is an important issue for breaking the chain of transmission of viral pathogens. Hydrogen peroxide has provided promising results in laboratory assays. Here, we evaluate the efficacy of a hydrogen peroxide nebulizer for the inactivation of surrogate MS2 bacteriophage and murine norovirus (MNV) in a patient waiting room and the fully equipped cabin of a medical ambulance. We observed an average 3 log₁₀ titer reduction in both settings, which represents the destruction of over 10⁶ and 10⁹ infectious particles of MNV and MS2 per cm², respectively. The potential for viral exposure is high for health workers when disinfecting confined and cluttered spaces, so the use of a hydrogen peroxide mist might offer an affordable and efficient solution to minimize the risk of viral contaminations.

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来源期刊

Food and Environmental Virology ENVIRONMENTAL SCIENCES-MICROBIOLOGY

CiteScore

6.50

自引率

2.90%

发文量

审稿时长

1 months

期刊介绍： Food and Environmental Virology publishes original articles, notes and review articles on any aspect relating to the transmission of pathogenic viruses via the environment (water, air, soil etc.) and foods. This includes epidemiological studies, identification of novel or emerging pathogens, methods of analysis or characterisation, studies on survival and elimination, and development of procedural controls for industrial processes, e.g. HACCP plans. The journal will cover all aspects of this important area, and encompass studies on any human, animal, and plant pathogenic virus which is capable of transmission via the environment or food.