从基因型到表型的小鼠基因组信息学(MGI)资源搜索

Q1 Biochemistry, Genetics and Molecular Biology
David R. Shaw
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引用次数: 9

摘要

小鼠基因组信息学(MGI)资源为研究团体提供了获取实验室小鼠遗传学、基因组学和生物学信息的途径。MGI的核心数据包括基因表征和功能、表型和疾病模型描述、DNA和蛋白质序列数据、基因表达数据、脊椎动物同源性、snp、制图数据以及与其他生物信息学数据库的链接。语义集成是通过使用标准化的命名法和受控词汇表(如小鼠解剖词典、哺乳动物表型本体论和基因本体论)来支持的。MGI从原始文献中提取和组织数据。MGI数据与其他生物信息学资源共享并广泛展示。该数据库每周更新一次,并定期添加新的数据集和功能。本单元提供了使用MGI生物信息学资源的指南。©2016 by John Wiley &儿子,Inc。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Searching the Mouse Genome Informatics (MGI) Resources for Information on Mouse Biology from Genotype to Phenotype

The Mouse Genome Informatics (MGI) resource provides the research community with access to information on the genetics, genomics, and biology of the laboratory mouse. Core data in MGI include gene characterization and function, phenotype and disease model descriptions, DNA and protein sequence data, gene expression data, vertebrate homologies, SNPs, mapping data, and links to other bioinformatics databases. Semantic integration is supported through the use of standardized nomenclature, and through the use of controlled vocabularies such as the mouse Anatomical Dictionary, the Mammalian Phenotype Ontology, and the Gene Ontologies. MGI extracts and organizes data from primary literature. MGI data are shared with and widely displayed from other bioinformatics resources. The database is updated weekly with curated annotations, and regularly adds new datasets and features. This unit provides a guide to using the MGI bioinformatics resource. © 2016 by John Wiley & Sons, Inc.

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来源期刊
Current protocols in bioinformatics
Current protocols in bioinformatics Biochemistry, Genetics and Molecular Biology-Biochemistry
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期刊介绍: With Current Protocols in Bioinformatics, it"s easier than ever for the life scientist to become "fluent" in bioinformatics and master the exciting new frontiers opened up by DNA sequencing. Updated every three months in all formats, CPBI is constantly evolving to keep pace with the very latest discoveries and developments.
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