用于光遗传学神经调控应用的基于无线驱动的3D打印头戴式神经刺激系统

IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC
Dipon K. Biswas;Nabanita Saha;Ifana Mahbub
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引用次数: 0

摘要

这项工作提出了一种小型化的无线功率传输(WPT)系统,该系统集成了神经调控头台,用于自由移动的啮齿类动物的负载循环光学刺激。所提出的WPT系统是使用市售的用于光遗传神经调控系统的现成组件(COTS)构建的,该系统由桥式整流器、DC-DC转换器、振荡电路、LED驱动器和μLED组成。刺激系统的总功耗为14mW,这是使用WPT方法提供的。WPT系统包括在印刷电路板(PCB)上实现的新型发射器(TX)线圈,以及缠绕在定制的3D打印头戴式耳机上的螺线管接收器(RX)线圈。所提出的TX线圈被设计为使得整个TX线圈上的磁场足以向光学刺激系统提供所需的功率,该光学刺激系统被自由移动的大鼠佩戴为头戴。头戴装置的尺寸为18.75 mm×21.95 mm,重量为4.75 g。头戴与大鼠的重量比为4.75:300。所提出的系统能够在TX和RX线圈之间5厘米的间隔处实现约63%的最大总效率,其中WPT系统的最大功率传输效率(PTE)为~88%,整流器的功率转换效率(PCE)为71.6%。所提出的具有可重构刺激频率的系统适用于刺激不同的大脑区域进行长期健康监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Wirelessly Powered 3-D Printed Headstage Based Neural Stimulation System for Optogenetic Neuromodulation Application
This work presents a miniaturized wireless power transfer (WPT) system integrated with a neuromodulation headstage for duty-cycled optical stimulation of freely moving rodents. The proposed WPT system is built using the commercially available off-the-shelf components (COTS) for the optogenetic neuromodulation system consisting of a bridge rectifier, a DC-DC converter, an oscillator circuit, an LED driver, and a μLED. The total power consumption of the stimulation system is 14 mW which is provided using the WPT method. The WPT system includes a novel transmitter (TX) coil implemented on a printed circuit board (PCB), and a solenoid receiver (RX) coil wrapped around a customized 3-D printed headstage. The proposed TX coil is designed in such a way that the magnetic field all across the TX coil is sufficient to provide the required power to the optical stimulation system that is worn as a headstage by the freely moving rat. The headstage device's dimension is 18.75 mm × 21.95 mm, weighing 4.75 g. The ratio of the weight of the headstage and rat is 4.75:300. The proposed system is able to achieve a maximum overall efficiency of ∼63% at 5 cm separation between the TX and RX coils, where the maximum power transfer efficiency (PTE) of the WPT system is ∼88% and the power conversion efficiency (PCE) of the rectifier is 71.6%. The proposed system with reconfigurable stimulation frequency is suitable for exciting different brain areas for long-term health monitoring.
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来源期刊
CiteScore
5.80
自引率
9.40%
发文量
58
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