高达40GHz的平面微芯片传感器对CHO和HepG2单细胞的表征

IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2023-03-23 DOI:10.1109/JERM.2023.3257480

Aleksandar Savić;Fabian Freiberger;Ralf Pörtner;Arne F. Jacob

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引用次数: 0

摘要

本文对CHO和HepG2细胞系的单个死细胞和活细胞进行了宽带微波测量。报告了分别用共面波导反射型和透射型传感器获得的结果。直接的单液体校准程序可以提取复介电常数，并将其与周围介质的介电常数进行比较。对比是通过$p$-value测试和通常的Cole-Cole参数来分析的。结果证明了基于介电常数的单元线的可分辨性。

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查看原文本刊更多论文

CHO and HepG2 Single-Cell Characterization With Planar Microchip Sensors up to 40 GHz

The article deals with broadband microwave measurements performed on single dead and living biological cells from CHO and HepG2 cell lines. It reports results obtained with coplanar waveguide reflection and transmission type sensors, respectively. A straight-forward single liquid calibration procedure allows to extract the complex cell permittivity and compare it to that of the surrounding medium. The contrast is analyzed through

$p$

-value tests and in terms of the usual Cole-Cole parameters. The results demonstrate the distinguishability of the cell lines based on the permittivity.

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来源期刊

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology ENGINEERING, ELECTRICAL & ELECTRONIC-

CiteScore

5.80

自引率

9.40%

发文量