可生物降解金属缝合锚:综述

Alireza Nouri , Anahita Rohani Shirvan , Yuncang Li , Cuie Wen
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引用次数: 7

摘要

缝合锚钉由于其易于插入、固定强度和体积小而被广泛用于将软组织连接到骨上。在过去的几十年里,缝合锚钉的材料和设计取得了巨大进步。它们最初是由不可生物降解的金属和聚合物制成的,但近年来,生物降解聚合物有了相当大的发展。生物可降解聚合物锚固件具有随着时间的推移逐渐降解、迁移风险最小化、翻修手术不那么复杂、无需移除手术以及改进术后成像等优点。然而,这些锚固件的固定强度低于金属锚固件,并且遭受不良的局部组织反应、炎症反应和快速降解。可生物降解金属似乎是未来缝合锚钉的理想候选者。它们具有高固定强度和接近骨骼的低弹性模量,这促进了骨整合,并允许设计更薄、更低体积的植入物。本文概述了可生物降解金属缝合锚的应用和制造,并总结了其在该领域的当前概念和性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Biodegradable metallic suture anchors: A review

Biodegradable metallic suture anchors: A review

Suture anchors are widely used for attaching soft tissue to bone due to their ease of insertion, fixation strength, and small size. The past few decades have seen great advances in the materials and designs of suture anchors. They were originally constructed of non-biodegradable metals and polymers, but in recent years there has been a considerable move toward biodegradable polymers. The biodegradable polymer anchors offer advantages such as gradual degradation over time, minimized risk of migration, less complex revision surgery, no need for a removal operation, and improved postsurgical imaging. However, these anchors have lower fixation strength than metal anchors and suffer from adverse local tissue reactions, inflammatory responses, and rapid degradation. Biodegradable metals appear to be ideal candidates for the future of suture anchors. They have high fixation strength and low elastic modulus close to that of bone, which promote osseointegration and allow the design of thinner and lower volume implants. The current article gives an overview of the application and manufacturing of biodegradable metallic suture anchors and summarizes their current concepts and properties in this area of continual development.

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