Zakia Belhadj, Yunkai Qie, Randy P. Carney, Yuanpei Li, Guangjun Nie
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Current advances in non-viral gene delivery systems: Liposomes versus extracellular vesicles
In article number 10.1002/bmm2.12018, Zakia Belhadj, Yunkai Qie, and their co-workers present a detailed comparison between liposomes (LSs) and extracellular vesicles (EVs) in the field of gene therapy. They summarize the advantages and limitations of these systems with particular emphasis on their in vivo fate and their advanced biomedical applications in nanomedicine. Additionally, they discuss the challenges facing the preclinical and clinical translation of these lipid-based nanocarriers, as well as their prospective use in the development of SARS-CoV-2 vaccines.
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