用于脑可植入柔性探针的生物可吸收插入助剂：丝纤维蛋白、海藻酸盐和二糖的比较研究

IF 4 Q2 ENGINEERING, BIOMEDICAL

Advanced Nanobiomed Research Pub Date : 2023-09-07 DOI:10.1002/anbr.202370091

Maria Cerezo-Sanchez, Eve McGlynn, Stefania Bartoletti, Bhavani Prasad Yalagala, Beatrice Casadei Garofani, Arianna Capodiferro, Ewan Russell, Gemma Palazzolo, Finlay Walton, Giulia Curia, Hadi Heidari

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引用次数: 0

摘要

植入式探针作为一种小型化、柔性和生物相容性的植入式神经探针，旨在规避异物反应，但由于屈曲而导致的手术植入问题仍然存在。Hadi Heidari及其同事在编号为2200117的文章中通过机械、化学和溶解特性对多种生物可吸收插入助剂进行了研究，以确定其作为新型柔性神经探针的硬化涂层的可行性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Bioresorbable Insertion Aids for Brain Implantable Flexible Probes: A Comparative Study on Silk Fibroin, Alginate, and Disaccharides

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Bioresorbable Insertion Aids for Brain Implantable Flexible Probes: A Comparative Study on Silk Fibroin, Alginate, and Disaccharides

Implantable Probes

As miniaturized, flexible, and biocompatible implantable neural probes seek to circumvent the foreign body response, the problem of surgical implantation due to buckling remains. Multiple bioresorbable insertion aids are investigated in article number 2200117 by Hadi Heidari and co-workers through mechanical, chemical and dissolution characterizations to determine their viability as stiffening coatings for novel flexible neural probes.

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来源期刊

Advanced Nanobiomed Research nanomedicine, bioengineering and biomaterials-

CiteScore

5.00

自引率

5.90%

发文量

审稿时长

21 weeks

期刊介绍： Advanced NanoBiomed Research will provide an Open Access home for cutting-edge nanomedicine, bioengineering and biomaterials research aimed at improving human health. The journal will capture a broad spectrum of research from increasingly multi- and interdisciplinary fields of the traditional areas of biomedicine, bioengineering and health-related materials science as well as precision and personalized medicine, drug delivery, and artificial intelligence-driven health science. The scope of Advanced NanoBiomed Research will cover the following key subject areas: ▪ Nanomedicine and nanotechnology, with applications in drug and gene delivery, diagnostics, theranostics, photothermal and photodynamic therapy and multimodal imaging. ▪ Biomaterials, including hydrogels, 2D materials, biopolymers, composites, biodegradable materials, biohybrids and biomimetics (such as artificial cells, exosomes and extracellular vesicles), as well as all organic and inorganic materials for biomedical applications. ▪ Biointerfaces, such as anti-microbial surfaces and coatings, as well as interfaces for cellular engineering, immunoengineering and 3D cell culture. ▪ Biofabrication including (bio)inks and technologies, towards generation of functional tissues and organs. ▪ Tissue engineering and regenerative medicine, including scaffolds and scaffold-free approaches, for bone, ligament, muscle, skin, neural, cardiac tissue engineering and tissue vascularization. ▪ Devices for healthcare applications, disease modelling and treatment, such as diagnostics, lab-on-a-chip, organs-on-a-chip, bioMEMS, bioelectronics, wearables, actuators, soft robotics, and intelligent drug delivery systems. with a strong focus on applications of these fields, from bench-to-bedside, for treatment of all diseases and disorders, such as infectious, autoimmune, cardiovascular and metabolic diseases, neurological disorders and cancer; including pharmacology and toxicology studies.