非编码RNA在生理和病理血管生成中的作用

IF 2.5 Q2 PHYSIOLOGY
Nihay Laham-Karam , Isidore Mushimiyimana , Krista Hokkanen , Seppo Ylä-Herttuala
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引用次数: 1

摘要

血管生成是建立新血管的过程,在生理学上很重要。此外,它还涉及不同的病理,包括癌症、局部缺血、黄斑变性和炎症性肠病。血管生成的调节是多方面的,根据最近的数据,包括增强子和非编码RNA的转录调节以及微小RNA的转录后调节。在这篇综述中,我们强调了该领域与生理和病理血管生成相关的最新发现,并讨论了对关键血管生成因子的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of non-coding RNAs in physiological and pathological angiogenesis

Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.

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来源期刊
Current Opinion in Physiology
Current Opinion in Physiology Medicine-Physiology (medical)
CiteScore
5.80
自引率
0.00%
发文量
52
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