非编码RNA在生理和病理血管生成中的作用

IF 2.5 Q2 PHYSIOLOGY
Nihay Laham-Karam , Isidore Mushimiyimana , Krista Hokkanen , Seppo Ylä-Herttuala
{"title":"非编码RNA在生理和病理血管生成中的作用","authors":"Nihay Laham-Karam ,&nbsp;Isidore Mushimiyimana ,&nbsp;Krista Hokkanen ,&nbsp;Seppo Ylä-Herttuala","doi":"10.1016/j.cophys.2023.100690","DOIUrl":null,"url":null,"abstract":"<div><p>Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.</p></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Role of non-coding RNAs in physiological and pathological angiogenesis\",\"authors\":\"Nihay Laham-Karam ,&nbsp;Isidore Mushimiyimana ,&nbsp;Krista Hokkanen ,&nbsp;Seppo Ylä-Herttuala\",\"doi\":\"10.1016/j.cophys.2023.100690\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.</p></div>\",\"PeriodicalId\":52156,\"journal\":{\"name\":\"Current Opinion in Physiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Opinion in Physiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2468867323000603\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHYSIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Physiology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468867323000603","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
引用次数: 1

摘要

血管生成是建立新血管的过程,在生理学上很重要。此外,它还涉及不同的病理,包括癌症、局部缺血、黄斑变性和炎症性肠病。血管生成的调节是多方面的,根据最近的数据,包括增强子和非编码RNA的转录调节以及微小RNA的转录后调节。在这篇综述中,我们强调了该领域与生理和病理血管生成相关的最新发现,并讨论了对关键血管生成因子的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of non-coding RNAs in physiological and pathological angiogenesis

Angiogenesis, the process of building new vessels, is important in physiology. In addition, it is involved in different pathologies, including cancers, ischemia, macular degeneration and inflammatory bowel disease. The regulation of angiogenesis is multifaceted and according to recent data includes transcriptional modulation by enhancers and non-coding RNAs as well as post-transcriptional regulation by microRNAs. In this review, we highlight recent findings in this field that relate both to physiological and pathological angiogenesis and discuss the effects on key angiogenic factors.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Current Opinion in Physiology
Current Opinion in Physiology Medicine-Physiology (medical)
CiteScore
5.80
自引率
0.00%
发文量
52
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信