一名CARD9缺乏症患者因紫丁香引起的淋巴结炎

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Medical Mycology Case Reports Pub Date : 2023-09-18 DOI:10.1016/j.mmcr.2023.100609

Hidetaka Majima , Yuzaburo Inoue , Yuichiro Otsuka , Takashi Yaguchi , Akira Watanabe , Katsuhiko Kamei

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引用次数: 0

摘要

我们在此首次报告一例由紫丁香引起的CARD9缺乏型真菌病。一位40岁的女性抱怨左侧颈部淋巴结肿大。她还患有慢性粘膜皮肤念珠菌感染（CMC），并被发现患有CARD9缺乏症。紫丁香属的淋巴腺炎已被证实。诊断很困难，因为需要在谨慎选择的温度（25°C）下培养活检标本和进行基因分析。口服伏立康唑改善了她的淋巴结病。

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Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency

We hereby make the first report of a case of mycosis caused by Purpureocillium lilacinum in CARD9 deficiency. A 40-year-old woman complained of lymph node swellings in the left cervical area. She also had chronic mucocutaneous candidiasis (CMC), and was found to have CARD9 deficiency. Lymphadenitis by P. lilacinum was confirmed. The diagnosis was difficult, as culturing the biopsy specimen at a cautiously selected temperature (25 °C) and genetic analysis were both required. Oral administration of voriconazole improved her lymphadenopathy.

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来源期刊

Medical Mycology Case Reports MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

4.00

自引率

0.00%

发文量

审稿时长

47 days