Lijun Cai , Ning Li , Yong Zhang , Hongcheng Gu , Yujuan Zhu
{"title":"口服给药用微流体衍生的微载体系统","authors":"Lijun Cai , Ning Li , Yong Zhang , Hongcheng Gu , Yujuan Zhu","doi":"10.1016/j.bmt.2022.11.001","DOIUrl":null,"url":null,"abstract":"<div><p>Oral delivery is with high patient compliance but low bioavailability and controllability. The emerging microfluidics-derived microcarriers have sprung up to relieve the hurdles. Herein, a review on the recent progress in applying microfluidics-derived microcarriers for oral delivery is presented. First, we briefly introduce the microfluidic fabrication of microcarriers based on laminar flow and droplets. Then, we focus on the applications of microfluidics-derived microcarriers for oral delivery in stomach, small intestine, and colon. Last but not least, we discuss the challenges and outlooks of the microfluidics-derived microparticles for oral delivery in the end. This review is anticipated to help readers to follow up the research frontiers in this field, and guide the future development direction of microfluidics-derived microcarriers.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"1 ","pages":"Pages 30-38"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"8","resultStr":"{\"title\":\"Microfluidics-derived microcarrier systems for oral delivery\",\"authors\":\"Lijun Cai , Ning Li , Yong Zhang , Hongcheng Gu , Yujuan Zhu\",\"doi\":\"10.1016/j.bmt.2022.11.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Oral delivery is with high patient compliance but low bioavailability and controllability. The emerging microfluidics-derived microcarriers have sprung up to relieve the hurdles. Herein, a review on the recent progress in applying microfluidics-derived microcarriers for oral delivery is presented. First, we briefly introduce the microfluidic fabrication of microcarriers based on laminar flow and droplets. Then, we focus on the applications of microfluidics-derived microcarriers for oral delivery in stomach, small intestine, and colon. Last but not least, we discuss the challenges and outlooks of the microfluidics-derived microparticles for oral delivery in the end. This review is anticipated to help readers to follow up the research frontiers in this field, and guide the future development direction of microfluidics-derived microcarriers.</p></div>\",\"PeriodicalId\":100180,\"journal\":{\"name\":\"Biomedical Technology\",\"volume\":\"1 \",\"pages\":\"Pages 30-38\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedical Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2949723X22000034\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Technology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949723X22000034","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Microfluidics-derived microcarrier systems for oral delivery
Oral delivery is with high patient compliance but low bioavailability and controllability. The emerging microfluidics-derived microcarriers have sprung up to relieve the hurdles. Herein, a review on the recent progress in applying microfluidics-derived microcarriers for oral delivery is presented. First, we briefly introduce the microfluidic fabrication of microcarriers based on laminar flow and droplets. Then, we focus on the applications of microfluidics-derived microcarriers for oral delivery in stomach, small intestine, and colon. Last but not least, we discuss the challenges and outlooks of the microfluidics-derived microparticles for oral delivery in the end. This review is anticipated to help readers to follow up the research frontiers in this field, and guide the future development direction of microfluidics-derived microcarriers.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
