胃癌在毛细胞白血病治疗中的不寻常表现:探讨这种罕见现象的病因学基础

Cancer pathogenesis and therapy Pub Date : 2023-04-01 DOI:10.1016/j.cpt.2023.01.003

Shahan Tariq , Muhammad Ammar Bin Hamid , Nazia Rahman , Lindsey Oleary , Kristine Wong , Aasim Sehbai

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引用次数: 0

摘要

毛细胞白血病（HCL）是一种罕见的B细胞淋巴增生性疾病。患者通常表现为血细胞减少和脾肿大。我们描述了一例78岁的难治性HCL患者，他在接受莫克西单抗-帕苏妥克斯治疗时，背部急性出现囊性病变。病变的活检显示存在腺癌，这促使进行详细评估，从而诊断为癌症IV期。尽管如此，为了确定莫昔单抗-帕苏妥昔治疗与继发性癌症发展之间的任何关联，需要进行令人满意的大量研究。

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Unusual presentation of gastric cancer during treatment of hairy cell leukemia: Exploring the etiological basis of this rare phenomenon

Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative disorder. Patients typically present with cytopenia and splenomegaly. We describe the case of a 78-year-old patient with refractory HCL who acutely developed a cystic lesion on the back while receiving moxetumomab pasudotox therapy. Biopsy of the lesion revealed the presence of adenocarcinoma, which prompted a detailed evaluation resulting in a diagnosis of stage IV gastric cancer. Nevertheless, to establish any association between moxetumomab pasudotox therapy and secondary cancer development, a satisfactory number of studies need to be conducted.

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来源期刊

Cancer pathogenesis and therapy Surgery, Radiology and Imaging, Cancer Research, Oncology

CiteScore

0.80

自引率

0.00%

发文量

审稿时长

54 days