Jie Zhang , Xiaorui Ma , Wei Wang , Caixia Wu , Ben Ma , Chong Yu , Haifeng Wang
{"title":"姜黄根中三个新的倍半萜化合物","authors":"Jie Zhang , Xiaorui Ma , Wei Wang , Caixia Wu , Ben Ma , Chong Yu , Haifeng Wang","doi":"10.1016/j.chmed.2022.11.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>To study the chemical constituents from the roots of <em>Curcuma longa</em>.</p></div><div><h3>Methods</h3><p>The structures of the compounds were elucidated based on extensive spectral analysis, including 1D and 2D NMR, MS, UV, and CD analysis.</p></div><div><h3>Results</h3><p>Two new sesquiterpene compounds (1<em>S</em>,2<em>R</em>,5<em>R</em>,7<em>S</em>,8<em>R</em>)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (<strong>1</strong>), (1<em>R</em>,2<em>R</em>,5<em>R</em>,7<em>S</em>,8<em>R</em>)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (<strong>2</strong>), and a new natural product 6-(4-Hydroxymethylphenyl)-2-methyl-hept-2-ene-4-one (<strong>3</strong>) together with three known compounds <em>ar</em>-turmerone (<strong>4</strong>), 2-methyl-6-(4-hydroxyphenyl-3-methyl)-2-hepten-4-one (<strong>5</strong>) and 2-methyl-6-(4-hydroxyphenyl)-2-hepten-4-one (<strong>6</strong>) were isolated from <em>C. longa</em> root extract with 95% ethanol.</p></div><div><h3>Conclusion</h3><p>In the study, three new compounds were isolated from <em>C. longa</em>, and their absolute configurations were determined.</p></div>","PeriodicalId":9916,"journal":{"name":"Chinese Herbal Medicines","volume":"15 3","pages":"Pages 470-474"},"PeriodicalIF":4.7000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Three new sesquiterpenes from roots of Curcuma longa\",\"authors\":\"Jie Zhang , Xiaorui Ma , Wei Wang , Caixia Wu , Ben Ma , Chong Yu , Haifeng Wang\",\"doi\":\"10.1016/j.chmed.2022.11.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>To study the chemical constituents from the roots of <em>Curcuma longa</em>.</p></div><div><h3>Methods</h3><p>The structures of the compounds were elucidated based on extensive spectral analysis, including 1D and 2D NMR, MS, UV, and CD analysis.</p></div><div><h3>Results</h3><p>Two new sesquiterpene compounds (1<em>S</em>,2<em>R</em>,5<em>R</em>,7<em>S</em>,8<em>R</em>)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (<strong>1</strong>), (1<em>R</em>,2<em>R</em>,5<em>R</em>,7<em>S</em>,8<em>R</em>)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (<strong>2</strong>), and a new natural product 6-(4-Hydroxymethylphenyl)-2-methyl-hept-2-ene-4-one (<strong>3</strong>) together with three known compounds <em>ar</em>-turmerone (<strong>4</strong>), 2-methyl-6-(4-hydroxyphenyl-3-methyl)-2-hepten-4-one (<strong>5</strong>) and 2-methyl-6-(4-hydroxyphenyl)-2-hepten-4-one (<strong>6</strong>) were isolated from <em>C. longa</em> root extract with 95% ethanol.</p></div><div><h3>Conclusion</h3><p>In the study, three new compounds were isolated from <em>C. longa</em>, and their absolute configurations were determined.</p></div>\",\"PeriodicalId\":9916,\"journal\":{\"name\":\"Chinese Herbal Medicines\",\"volume\":\"15 3\",\"pages\":\"Pages 470-474\"},\"PeriodicalIF\":4.7000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chinese Herbal Medicines\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1674638423000503\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Herbal Medicines","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1674638423000503","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
Three new sesquiterpenes from roots of Curcuma longa
Objective
To study the chemical constituents from the roots of Curcuma longa.
Methods
The structures of the compounds were elucidated based on extensive spectral analysis, including 1D and 2D NMR, MS, UV, and CD analysis.
Results
Two new sesquiterpene compounds (1S,2R,5R,7S,8R)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (1), (1R,2R,5R,7S,8R)-2,8-epoxy-5-hydroxybisabola-3,10-dioen-9-one (2), and a new natural product 6-(4-Hydroxymethylphenyl)-2-methyl-hept-2-ene-4-one (3) together with three known compounds ar-turmerone (4), 2-methyl-6-(4-hydroxyphenyl-3-methyl)-2-hepten-4-one (5) and 2-methyl-6-(4-hydroxyphenyl)-2-hepten-4-one (6) were isolated from C. longa root extract with 95% ethanol.
Conclusion
In the study, three new compounds were isolated from C. longa, and their absolute configurations were determined.
期刊介绍：
Chinese Herbal Medicines is intended to disseminate the latest developments and research progress in traditional and herbal medical sciences to researchers, practitioners, academics and administrators worldwide in the field of traditional and herbal medicines. The journal's international coverage ensures that research and progress from all regions of the world are widely included.
CHM is a core journal of Chinese science and technology. The journal entered into the ESCI database in 2017, and then was included in PMC, Scopus and other important international search systems. In 2019, CHM was successfully selected for the “China Science and Technology Journal Excellence Action Plan” project, which has markedly improved its international influence and industry popularity. CHM obtained the first impact factor of 3.8 in Journal Citation Reports (JCR) in 2023.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
