JAK2阴性红细胞增多症ST段抬高心肌梗死和出血并发症。

IF 0.9 4区医学

Texas Heart Institute Journal Pub Date : 2023-10-20 DOI:10.14503/THIJ-23-8148

Priscilla Duran Luciano, Vanessa Sabella-Jiménez

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引用次数: 0

摘要

血栓和出血并发症是真性红细胞增多症患者发病率和死亡率的主要原因，这些患者主要表现为JAK2基因的改变。由于其高凝状态和出血风险，出现急性心肌梗死的真性红细胞增多症患者对医生构成了挑战。本病例报告描述了一名患有JAK2 V617F阴性原发性红细胞增多症的西班牙裔患者的表现和治疗，该患者因左前降支完全闭塞、出血并发症和心肌后心包炎而出现心脏骤停和ST段抬高心肌梗死。

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ST-Segment Elevation Myocardial Infarction and Bleeding Complications in JAK2-Negative Polycythemia.

Thrombotic and bleeding complications are major causes of morbidity and mortality in patients with polycythemia vera, who predominantly present with an alteration in the JAK2 gene. Because of their hypercoagulable state and risk of hemorrhage, patients with polycythemia vera who present with an acute myocardial infarction pose a challenge to physicians. This case report describes the presentation and treatment of a Hispanic patient with JAK2 V617F-negative primary polycythemia who developed cardiac arrest and ST-segment elevation myocardial infarction owing to complete occlusion of the left anterior descending artery as well as bleeding complications and postmyocardial pericarditis.

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来源期刊

Texas Heart Institute Journal CARDIAC & CARDIOVASCULAR SYSTEMS-

自引率

11.10%

发文量

131

期刊介绍： For more than 45 years, the Texas Heart Institute Journal has been published by the Texas Heart Institute as part of its medical education program. Our bimonthly peer-reviewed journal enjoys a global audience of physicians, scientists, and healthcare professionals who are contributing to the prevention, diagnosis, and treatment of cardiovascular disease. The Journal was printed under the name of Cardiovascular Diseases from 1974 through 1981 (ISSN 0093-3546). The name was changed to Texas Heart Institute Journal in 1982 and was printed through 2013 (ISSN 0730-2347). In 2014, the Journal moved to online-only publication. It is indexed by Index Medicus/MEDLINE and by other indexing and abstracting services worldwide. Our full archive is available at PubMed Central. The Journal invites authors to submit these article types for review: -Clinical Investigations- Laboratory Investigations- Reviews- Techniques- Coronary Anomalies- History of Medicine- Case Reports/Case Series (Submission Fee: $70.00 USD)- Images in Cardiovascular Medicine (Submission Fee: $35.00 USD)- Guest Editorials- Peabody’s Corner- Letters to the Editor