位点特异性放射性标记的纳米体，用于对脑中血脑屏障的穿透和靶向进行成像。

IF 0.9 4区医学 Q4 BIOCHEMICAL RESEARCH METHODS

Journal of labelled compounds & radiopharmaceuticals Pub Date : 2023-10-24 DOI:10.1002/jlcr.4069

Yingbo Li, Junfeng Wang

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引用次数: 0

摘要

纳米体由于其独特的特性在分子成像中具有巨大的潜力。然而，当涉及到大脑成像时，还有一些挑战需要克服。为了解决这些障碍，需要进行合作和跨学科研究。这篇文章旨在提高人们的认识，鼓励来自各个领域的研究人员合作，寻找使用Nbs进行有效大脑成像的解决方案。通过促进合作和知识共享，我们可以在克服现有限制方面取得进展，并为未来改进分子成像技术铺平道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Site-specifically radiolabeled nanobodies for imaging blood-brain barrier penetration and targeting in the brain

Nanobodies (Nbs) hold significant potential in molecular imaging due to their unique characteristics. However, there are challenges to overcome when it comes to brain imaging. To address these obstacles, collaborative efforts and interdisciplinary research are needed. This article aims to raise awareness and encourage collaboration among researchers from various fields to find solutions for effective brain imaging using Nbs. By fostering cooperation and knowledge sharing, we can make progress in overcoming the existing limitations and pave the way for improved molecular imaging techniques in the future.

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来源期刊

Journal of labelled compounds & radiopharmaceuticals 医学-分析化学

CiteScore

3.30

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： The Journal of Labelled Compounds and Radiopharmaceuticals publishes all aspects of research dealing with labeled compound preparation and applications of these compounds. This includes tracer methods used in medical, pharmacological, biological, biochemical and chemical research in vitro and in vivo. The Journal of Labelled Compounds and Radiopharmaceuticals devotes particular attention to biomedical research, diagnostic and therapeutic applications of radiopharmaceuticals, covering all stages of development from basic metabolic research and technological development to preclinical and clinical studies based on physically and chemically well characterized molecular structures, coordination compounds and nano-particles.