一例与强直性脊柱炎初始表现相关的中性粒细胞和肉芽肿性皮炎。

Young Sun Suh, Eui Chang Jung, Yun Sun Moon, Seung-Geun Lee, Hyun-Ok Kim
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引用次数: 1

摘要

帕利塞德中性粒细胞和肉芽肿性皮炎(PNGD)是一种炎症性皮肤病,与类风湿性关节炎、系统性硬化症、红斑狼疮和溃疡性结肠炎等系统免疫介导的疾病有关。组织学上,白细胞碎屑性血管炎从早期开始就表现出一系列的发展,在完全发展阶段可以发展为栅栏状肉芽肿,在最后阶段可以发展成纤维化。一位32岁的男性,表现为强直性脊柱炎,手指、肘部、膝盖和左耳廓出现多处红斑丘疹。他的皮肤病变的组织学检查显示有穿孔栅栏肉芽肿伴白细胞碎屑血管炎,这与PNGD一致。因此,本研究报告了一例PNGD伴强直性脊柱炎的初步表现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case of Palisaded Neutrophilic and Granulomatous Dermatitis Associated with an Initial Presentation in Ankylosing Spondylitis.

Palisaded neutrophilic and granulomatous dermatitis (PNGD) is an inflammatory dermatosis associated with systemic immune-mediated diseases such as rheumatoid arthritis, systemic sclerosis, lupus erythematosus, and ulcerative colitis. Histologically, serial development of leukocytoclastic vasculitis is shown from an early stage, which can progress to palisading granuloma in the fully developed stage and to fibrosis in the final stage. A 32-year-old man presented with ankylosing spondylitis showing multiple erythematous papules on his fingers, elbows, knees, and left auricle. Histologic examination from his skin lesion revealed a perforating palisading granuloma with leukocytoclastic vasculitis, which was consistent with PNGD. Therefore, this study reported a case of PNGD accompanied by ankylosing spondylitis as an initial presentation.

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