外周动脉粥样硬化重建干预后急性肾功能障碍的模式可以被认为是可预期的吗?

Q4 Biochemistry, Genetics and Molecular Biology
N. I. Glushkov, I. A. Kostyle, M. D. Naidenova, A. A. Borodich, M. A. Troyno, A. Novik, L. S. Bakhtigareeva, M. A. Ivanov
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引用次数: 0

摘要

进行了一项原始研究,确定了易患急性肾功能不全(ARD)的风险因素,确定了下肢血运重建手术后发生ARD的频率和后果,并研究和总结了有关该主题的科学文章中的数据。本研究的目的是调查因外周动脉疾病而进行血运重建的患者发生ARD的风险情况。材料和方法。对101例因外周动脉粥样硬化(包括动脉瘤性疾病)在主动脉-髂段手术的患者进行了ARD发展的前瞻性研究。在40名患者中观察到根据RIFLE建议登记的ARD表现。分析血液动力学参数、肌酸酐水平、利尿、合并疾病和术后病程。后果在糖尿病、心脏病理和全身动脉粥样硬化表现的患者以及紧急干预后,ARD的发生率显著较高。在血液动力学不稳定和失血超过1000ml的背景下,包括血液循环集中的表现,ARD的概率尤其高。结论。伴有血液动力学不稳定表现的大量失血,以及心脏疾病,对主动脉-髂段手术后ARD的发展有决定性影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Can the patterns of acute renal dysfunction after reconstructive interventions for peripheral atherosclerosis be considered expectable?
An original study was conducted and risk factors predisposing to the development of acute renal dysfunction (ARD) were identified, the frequency and consequences of ARD after revascularization operations on the lower extremities were established, and data from scientific articles on this topic were studied and summarized. The aim of the study was to investigate the circumstances of the risk of ARD in patients who underwent revascularization due to peripheral arterial disease.Material and methods. The signs of ARD development were prospectively studied in 101 patients operated on the aorto-iliac segment for peripheral atherosclerosis, including aneurysmal disease. Manifestations of ARD registered according to RIFLE recommendations were observed in 40 patients. Hemodynamic parameters, creatinine levels, diuresis, concomitant diseases, and the course of the postoperative period were analyzed.Results. The incidence of ARD was significantly higher in persons with diabetes mellitus, cardiac pathology and manifestations of generalized atherosclerosis, as well as after emergency interventions. The probability of ARD is especially high against the background of hemodynamic instability and blood loss of more than 1000 ml, including with manifestations of centralization of blood circulation.Conclusions. Massive blood loss with manifestations of hemodynamic instability, as well as cardiac disorders, has a decisive influence on the development of ARD after operations on the aorto-iliac segment.
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CiteScore
0.40
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审稿时长
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