琼脂及其复合材料的生物医学应用综述

IF 0.7 Q4 CHEMISTRY, MEDICINAL

Natural Products Journal Pub Date : 2022-06-15 DOI:10.2174/2210315512666220615113320

G. Surendran, A. Sherje

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引用次数: 1

摘要

琼脂是一种柔性的生物聚合物，与水混合后会形成果冻状的稠度。它是通过碱处理从海藻中提取的，也可以由6-磷酸果糖合成。琼脂及其复合材料被发现在药物递送、伤口愈合、肿瘤治疗和热疗中有应用。琼脂凝胶制剂已经用于超声成像，因为它具有散射声波的能力。研究表明，琼脂具有作为药物缓释基质的能力。琼脂/胶原复合物被发现可用于伤口、烧伤和溃疡的愈合。琼脂还具有作为羰基铁基质的能力，发现羰基铁具有良好的导热性，并可用于治疗热疗。本文综述了琼脂及其复合材料的性质、来源、生物合成、提取及近年来的生物医学应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biomedical Applications of Agar and its Composites: A Mini-Review

Agar is a flexible biopolymer that forms jelly like consistency when mixed with water. It is extracted from seaweeds by treatment with alkali and can also be synthesized from fructose-6-phosphate. Agar and its composites were found to have applications in drug delivery, wound healing, tumour therapy and hyperthermia treatment. Agar gel formulations have been used for ultrasound imaging since it has the ability to scatter sound waves. It has been investigated that agar has the ability to act as a matrix for modified release of drugs. Agar/collagen composites were found to be useful in healing of wounds, burns and ulcers. Agar also has the ability to act as a matrix for carbonyl iron which is found to have a good thermal conductivity and became useful for the treatment of hyperthermia. This review summarizes the properties, sources, biosynthesis, extraction and recent biomedical applications of agar and its composites.

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来源期刊

Natural Products Journal CHEMISTRY, MEDICINAL-

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： The Natural Products Journal a peer reviewed journal, aims to publish all the latest and outstanding developments in natural products. The Natural Products Journal publishes original research articles, full-length/mini reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.