冠状动脉内膜切除术——一种完成血运重建的方法

Q4 Medicine
H. Patel, Ishan Gohil, J. Kothari, P. Shah
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引用次数: 0

摘要

研究的背景和目的:冠状动脉内膜切除术(CE)是在冠状动脉旁路移植术(CABG)移植术的旁边进行的,以帮助完成血运重建。然而,CE在弥漫性冠状动脉疾病(CAD)外科治疗中的作用存在争议。本研究的目的是强调与CE相关的手术结果、安全性和并发症。方法:在我所心血管胸外科进行观察性前瞻性研究。对2019年至2021年接受隔离CABG+CE的所有患者进行评估。接受紧急、紧急或选择性CABG+CE非体外循环/体外循环手术的患者被纳入研究。结果:100例CABG+CE患者根据症状进行了评估,并进行了连续心电图监测和血液样本中心脏生物标志物的检测。在手术后6、12、24、48和72小时采集血样。85名患者需要单次CE,15名患者需要双次CE。我们注意到心脏标志物在前6小时呈上升趋势,在24小时达到峰值,在手术后72小时呈下降趋势。尽管患者的心脏生物标志物值大幅上升,但临床患者病情稳定,手术死亡率为5%。结论:我们相信CE有助于弥漫性CAD患者的完全血运重建。在一个因其复杂性和随之而来的神话而被忽视的时代,行政长官应该得到应有的考虑。CE是外科医生医疗器械中一种重要而不可或缺的武器,我们不应该因为相关的神话而犹豫是否进行CE。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Coronary endarterectomy – A way to complete revascularization
Background and Aim of the Study: Coronary endarterectomy (CE) is performed adjacent to coronary artery bypass grafting (CABG) grafting to aid complete revascularization. However, the purpose of CE in surgical management of diffuse coronary artery disease (CAD) is controversial. The objective of this study was to highlight the operative outcomes, safety, and complications associated with CE. Methods: An observational, prospective research was carried out in the Department of Cardiovascular and Thoracic Surgery at our institute. All patients undergoing isolated CABG + CE from 2019 till 2021 were evaluated. Patients undergoing urgent, emergency, or elective CABG + CE off-pump/on-pump surgery were enrolled. Results: One hundred patients with CABG + CE were evaluated based on symptomatology with sequential electrocardiogram monitoring and blood samples for cardiac biomarkers. The blood samples were taken 6, 12, 24, 48, and 72 h following surgery. Eighty-five patients required single CE and 15 patients required double CE. We noticed a rising trend of cardiac markers in the first 6 h, reaching its peak level at 24 h, and downward trend following 72 h following surgery. Although patients had a tremendous rise in the cardiac biomarker values, clinically patients were stable with operative mortality of 5%. Conclusions: We believe CE helps in complete revascularization in patients with diffuse CAD. CE should be given due consideration in an era where it has been neglected due to its complexities and accompanying myths. CE is an important and integral weapon in a surgeon's armamentarium, and we should not hesitate to perform CE due to associated myths.
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CiteScore
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27 weeks
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