儿童肺动脉高压患者从静脉注射到皮下注射曲前列素的转变

Q4 Medicine

Clinical Pulmonary Medicine Pub Date : 2020-03-01 DOI:10.1097/CPM.0000000000000355

Sally J. Rockwell, Joe Miller, B. Brown, Amy L. Kiskaddon, Frances Gilliland, G. Freire, Daniel A. Mauriello

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引用次数: 0

摘要

肺动脉高压（PH）在儿童中引起显著的发病率和死亡率，尽管对成人肺动脉高压的治疗策略进行了充分的研究和开发，但很少有关于儿童患者的数据。在成年患者中，有报道称从静脉注射（IV）依前列醇到皮下注射（SC）曲前列素的成功过渡，但这一信息仅限于儿科患者。此外，虽然有成人SC至IV型曲前列素的报告，但没有从IV型转SC型曲前列肽的报告。本病例报告叙述了一例世界卫生组织3级PH继发于间质性肺病的儿科患者从静脉注射曲前列素成功过渡到SC曲前列素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Transition From Intravenous to Subcutaneous Treprostinil in a Pediatric Patient With Pulmonary Hypertension

Pulmonary hypertension (PH) causes significant morbidity and mortality in children, and, while the treatment strategies for PH in adults are well studied and developed, few data exist for pediatric patients. In adult patients, successful transitions from intravenous (IV) epoprostenol to subcutaneous (SC) treprostinil are reported, but this information is limited for pediatric patients. Furthermore, while there are reports of SC to IV treprostinil in adults, there are no reports of the transition from IV to SC treprostinil. This case report recounts a successful transition from IV treprostinil to SC treprostinil in a pediatric patient with WHO Class 3, PH, secondary to interstitial lung disease.

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来源期刊

Clinical Pulmonary Medicine Medicine-Critical Care and Intensive Care Medicine

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期刊介绍： Clinical Pulmonary Medicine provides a forum for the discussion of important new knowledge in the field of pulmonary medicine that is of interest and relevance to the practitioner. This goal is achieved through mini-reviews on focused sub-specialty topics in areas covered within the journal. These areas include: Obstructive Airways Disease; Respiratory Infections; Interstitial, Inflammatory, and Occupational Diseases; Clinical Practice Management; Critical Care/Respiratory Care; Colleagues in Respiratory Medicine; and Topics in Respiratory Medicine.