Chaetomorpha linum的抗氧化、抗菌作用及其预防治疗绿脓杆菌感染的毒理学评价

IF 1.3 Q3 FISHERIES

Journal of Applied Aquaculture Pub Date : 2021-08-19 DOI:10.1080/10454438.2021.1961966

S. Thanigaivel, John Thomas, A. Vickram, G. Gulothungan, R. Nanmaran, D. Jenila Rani

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引用次数: 1

摘要

摘要研究了毛藻水提取物和乙醇提取物对铜绿假单胞菌感染的抗氧化活性和抗菌效果。体外和体内研究揭示了C.linum乙醇提取物在控制铜绿假单胞菌感染方面的功效。还对乙醇提取物的纯化级分进行了气相色谱-质谱分析。对纯化的海藻提取物进行了鱼类毒性生物测定，以评估其对罗湖鱼的毒性作用，发现其无毒。铜绿假单胞菌的实验致病性表现为眼球突出、饲料摄入量减少和身体损伤。在实验致病性中，LD50在48小时达到3.96×102，在72小时达到4.82×103。结果表明，亚麻乙醇提取物可作为控制绿脓杆菌感染的替代来源。

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Antioxidant and antibacterial efficacy of Chaetomorpha linum and its toxicological evaluation for the prophylactic treatment against Pseudomonas aeruginosa infection in Labeo rohita

ABSTRACT The antioxidant activity and antibacterial efficacy of aqueous and ethanolic extracts of Chaetomorpha linum were tested against bacterial infection caused by Pseudomonas aeruginosa. In vitro and in vivo studies revealed the efficacy of ethanolic extract of C. linum in controlling the P. aeruginosa infection. Gas Chromatography Mass Spectroscopy analysis of purified fractions of ethanolic extract was also performed. Ichthyotoxic bioassay of purified seaweed extracts was performed to assess its toxic effect in rohu fish and found to be nontoxic. Experimental pathogenicity of P. aeruginosa showed exophthalmia, reduced intake of feed, and lesions on the body. LD 50 was achieved at the 3.96 × 102 at 48 h and 4.82 × 103 at 72 h in the experimental pathogenicity. The results revealed that the ethanolic extract of C. linum can be used as an alternate source for controlling P. aeruginosa infection in L. rohita.

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来源期刊

Journal of Applied Aquaculture Environmental Science-Ecology

CiteScore

3.20

自引率

0.00%

发文量

期刊介绍： The Journal of Applied Aquaculture is a platform for the sharing of practical information needed by researchers to meet the needs of investors, farm managers, extension agents and policy makers working to adapt aquaculture theory to achieve economic and food security objectives in the real world. The journal emphasizes multi-disciplinary research and case studies that propose financially and logistically viable solutions to observable problems.