EEF1E1（真核翻译延伸因子1ε1）

Q4 Medicine

Atlas of Genetics and Cytogenetics in Oncology and Haematology Pub Date : 2020-06-01 DOI:10.4267/2042/70858

L. Cristiano

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引用次数: 0

摘要

真核翻译延伸因子1ε1，别名EEF1E1，是一种蛋白质编码基因，在翻译的延伸步骤中发挥作用。特别地，它是大分子氨酰基tRNA合成酶复合物（MARS）的辅助成分。它在人类癌症细胞中的表达经常发生改变，被认为是公认的肿瘤抑制基因。这篇综述收集了有关DNA/RNA、编码的蛋白质以及EEF1E1所涉及的疾病的数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1)

Eukaryotic translation elongation factor 1 epsilon 1, alias EEF1E1, is a protein-coding gene that plays a role in the elongation step of translation. In particular, it is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex (MARS). Its expression is found frequently altered in human cancer cells and it is considered a putative tumor suppressor gene. This review collects the data on DNA/RNA, the protein encoded and the diseases where EEF1E1 is involved.

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来源期刊

Atlas of Genetics and Cytogenetics in Oncology and Haematology Medicine-Oncology

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