新冠肺炎肾脏损害的流行病学、临床和形态学研究

IF 0.2 Q4 UROLOGY & NEPHROLOGY

Journal of Renal Injury Prevention Pub Date : 2021-04-02 DOI:10.34172/jrip.2021.17

B. Daminov, S. Abdullaev, O. Sharapov, R. Igamberdieva

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引用次数: 2

摘要

小型综述介绍了新冠肺炎肾脏损伤的流行病学、临床和形态学方面的现代数据。肾脏参与该疾病临床表现的潜在机制可能包括细胞因子损伤、跨器官损伤和决定治疗策略的全身效应。这些机制密切相关，对接受体外治疗和肾移植的个体尤其重要。尸检数据提供了严重新冠肺炎患者严重急性呼吸系统综合征冠状病毒2型病毒侵入肾组织，肾小管上皮细胞和足细胞受损，红细胞聚集的证据。通过将慢性肾脏疾病患者纳入计划的新冠肺炎研究方案，可以为有效和安全的治疗建立证据基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Epidemiological, clinical and morphological aspects of kidney damage in COVID-19

The mini-review presents modern data on the epidemiology, clinical and morphological aspects of kidney damage in COVID-19. Potential mechanisms of kidney involvement in the clinical picture of the disease may include cytokine damage, cross-organ damage, and systemic effects that determine the treatment strategy. These mechanisms are closely interrelated and are especially important for individuals undergoing extracorporeal therapy and kidney transplants. Autopsy data provide evidence of SARS-CoV-2 virus invasion into kidney tissue with damage to tubular epithelial cells and podocytes, and erythrocyte aggregation in persons with severe COVID-19. By including people with chronic kidney disease in planned COVID-19 research protocols, an evidence base for effective and safe treatments can be generated.

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来源期刊

Journal of Renal Injury Prevention UROLOGY & NEPHROLOGY-

CiteScore

1.60

自引率

0.00%

发文量

期刊介绍： The Journal of Renal Injury Prevention (JRIP) is a quarterly peer-reviewed international journal devoted to the promotion of early diagnosis and prevention of renal diseases. It publishes in March, June, September and December of each year. It has pursued this aim through publishing editorials, original research articles, reviews, mini-reviews, commentaries, letters to the editor, hypothesis, case reports, epidemiology and prevention, news and views and renal biopsy teaching point. In this journal, particular emphasis is given to research, both experimental and clinical, aimed at protection/prevention of renal failure and modalities in the treatment of diabetic nephropathy. A further aim of this journal is to emphasize and strengthen the link between renal pathologists/nephropathologists and nephrologists. In addition, JRIP welcomes basic biomedical as well as pharmaceutical scientific research applied to clinical nephrology. Futuristic conceptual hypothesis that integrate various fields of acute kidney injury and renal tubular cell protection are encouraged to be submitted.