Aggressive well differentiated invasive ductal carcinoma twelve years after bilateral mastectomies for invasive lobular carcinoma

Ductal and lobular breast neoplasms represent morphologically distinct entities. Ductal breast carcinoma may involve lobules and lobular carcinoma may involve ducts. Invasive lobular carcinoma is difficult to diagnose on screening mammogram since it often does not form a mass lesion in contrast to ductal breast cancer [13]. It may present as an area of thickening or change in texture [4]. Lobular neoplasia includes atypical lobular hyperplasia, lobular carcinoma in situ (LCIS) and invasive lobular carcinoma.