{"title":"促肾上腺皮质激素（ACTH）在慢性疼痛中的作用","authors":"Forest Tennant","doi":"10.1111/jabr.12063","DOIUrl":null,"url":null,"abstract":"<div>\n <p>To determine if severe, chronic, uncontrolled pain patients may alter their adrenocorticotropin (ACTH) serum levels. Fifty-five (55) severe, chronic pain patients who were failing standard medical treatment were tested for an ACTH serum level. Those patients with an abnormal (high or low) serum level were entered into an enhanced pain treatment program and retested in 90–120 days to help determine if pain treatment may normalize abnormal ACTH serum levels. Five (9.4%) patients had a high ACTH serum level, and ten (18.2%) patients had a low ACTH serum level. Of these 15 patients, 13 (86.7%) normalized their ACTH serum levels after 90–120 days of enhanced treatment. The remaining two patients were found to have organic hypopituitarism secondary to traumatic brain injury. Severe, chronic pain may alter serum ACTH levels, and enhanced treatment may normalize serum levels.</p>\n </div>","PeriodicalId":45868,"journal":{"name":"JOURNAL OF APPLIED BIOBEHAVIORAL RESEARCH","volume":"22 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2017-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jabr.12063","citationCount":"3","resultStr":"{\"title\":\"Adrenocorticotropin (ACTH) in Chronic Pain\",\"authors\":\"Forest Tennant\",\"doi\":\"10.1111/jabr.12063\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n <p>To determine if severe, chronic, uncontrolled pain patients may alter their adrenocorticotropin (ACTH) serum levels. Fifty-five (55) severe, chronic pain patients who were failing standard medical treatment were tested for an ACTH serum level. Those patients with an abnormal (high or low) serum level were entered into an enhanced pain treatment program and retested in 90–120 days to help determine if pain treatment may normalize abnormal ACTH serum levels. Five (9.4%) patients had a high ACTH serum level, and ten (18.2%) patients had a low ACTH serum level. Of these 15 patients, 13 (86.7%) normalized their ACTH serum levels after 90–120 days of enhanced treatment. The remaining two patients were found to have organic hypopituitarism secondary to traumatic brain injury. Severe, chronic pain may alter serum ACTH levels, and enhanced treatment may normalize serum levels.</p>\\n </div>\",\"PeriodicalId\":45868,\"journal\":{\"name\":\"JOURNAL OF APPLIED BIOBEHAVIORAL RESEARCH\",\"volume\":\"22 3\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-04-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1111/jabr.12063\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JOURNAL OF APPLIED BIOBEHAVIORAL RESEARCH\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/jabr.12063\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Social Sciences\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JOURNAL OF APPLIED BIOBEHAVIORAL RESEARCH","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jabr.12063","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Social Sciences","Score":null,"Total":0}
To determine if severe, chronic, uncontrolled pain patients may alter their adrenocorticotropin (ACTH) serum levels. Fifty-five (55) severe, chronic pain patients who were failing standard medical treatment were tested for an ACTH serum level. Those patients with an abnormal (high or low) serum level were entered into an enhanced pain treatment program and retested in 90–120 days to help determine if pain treatment may normalize abnormal ACTH serum levels. Five (9.4%) patients had a high ACTH serum level, and ten (18.2%) patients had a low ACTH serum level. Of these 15 patients, 13 (86.7%) normalized their ACTH serum levels after 90–120 days of enhanced treatment. The remaining two patients were found to have organic hypopituitarism secondary to traumatic brain injury. Severe, chronic pain may alter serum ACTH levels, and enhanced treatment may normalize serum levels.
期刊介绍：
The Journal of Applied Biobehavioral Research, launched in 1993, aims to disseminate findings of behavioral science research which have applications to current problems of society. By publishing relevant research and emphasizing the excellence of experimental design, as well as potential applicability of experimental results, the journal bridges the theoretical and applied areas of biobehavioral research. The Journal of Applied Biobehavioral Research serves as a means of communication among scientists, as well as between researchers and those engaged in the task of solving social and biomedical problems.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
