一例HIV感染儿童的侵袭性肺曲霉菌病

Q4 Medicine

HIV Infection and Immunosuppressive Disorders Pub Date : 2022-01-28 DOI:10.22328/2077-9828-2021-13-4-96-100

E. Krasnova, G. S. Karpovich, D. Kapustin, I. V. Kuimova, I. Izvekova, E. N. Kibireva, A. Shestakov, S. G. Bychkov, E. P. Shilova, L. V. Poddubnaya

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引用次数: 0

摘要

侵袭性肺曲霉菌病（IPA）是一种罕见的疾病，主要发生在免疫功能低下的患者中。目前，肿瘤血液病、自身免疫性病理的患者数量稳步增加，需要新的高效免疫抑制治疗，然而，HIV感染仍然是免疫抑制发展的主要原因之一。尽管在研究与艾滋病毒感染有关的问题方面取得了进展，但许多问题，特别是与这种疾病的病程和儿童继发感染有关的许多问题仍未解决。其中之一是侵袭性真菌病，包括PLA。本文介绍了IPA在一名7岁新诊断的HIV感染患者中的临床观察，证明了诊断和治疗此类疾病的困难。

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Invasive pulmonary aspergilosis in a child with HIV infection

Invasive pulmonary aspergillosis (IPA) is a rare disease occurring mainly in immunocompromised patients. Currently, there is a steady increase in the number of patients with oncohematological diseases, autoimmune pathology, requiring new highly effective immunosuppressive therapy, however, HIV infection remains one of the main reasons for the development of immunosuppression. Despite the progress made in studying issues related to HIV infection, many problems, especially in relation to the course of this disease and secondary infections in children, remain unresolved. One of them is invasive mycosis, including PLA. The article presents a clinical observation of IPA in a 7-year-old patient with newly diagnosed HIV infection, demonstrates the difficulties of diagnosing and treating such conditions.

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来源期刊

HIV Infection and Immunosuppressive Disorders Medicine-Infectious Diseases

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： In the scientific-practical journal "HIV Infection and Immunosuppressive Disorders", published various issues of HIV medicine (epidemiology, molecular mechanisms of pathogenesis to the development of educational programs) leading scientists of Russia and countries of CIS, USA, as well as practical healthcare professionals working in research centers, research institutes, universities, clinics where done basic medical work. A special place on the pages of the publication is given to basic and clinical research, analytical reviews of contemporary and foreign reports, the provision of medical care for various diseases.