先天性B细胞免疫在癌症预防中的核心作用

生物化学进展(英文) Pub Date : 2021-01-13 DOI:10.4236/ABC.2021.111002

N. Tupitsyn

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引用次数: 0

摘要

有些东西被遗忘了。有一种特殊的方法可以在癌症细胞出现的早期阶段根除它们。CD5+B细胞的自然体液免疫通常产生对癌症相关聚糖的五聚体IgM，以消除正在发生的癌症细胞。先天免疫的这一分支随着年龄的增长而减少，这是选择性免疫缺陷的基础，可以纠正。Vollmers教授（德国）的团队对这一研究领域进行了充分的研究和证明，但随后被遗忘了大约15年。

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Central Role of Innate B-Cell Immunity in Cancer Prevention

There are some forgotten items. There is a specific way to eradicate cancer cells at the very early stage of their appearance. Natural humoral immunity with CD5+ B-cell produced pentameric IgM to cancer associated glycans normally to eliminate arising cancer cells. This branch of innate immunity is decreasing with age and that is a basis for selective immunodeficieny which may be corrected. This area of research was well studied and proved by the team of Prof. Vollmers (Germany), but then forgotten for about 15 years.

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生物化学进展(英文)

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