非特异性溃疡性结肠炎与新冠肺炎病例研究

Z. P. Lemeshevskaya, M. V. Pavlukevich, N. I. Procopchik
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引用次数: 1

摘要

背景当与各种躯体疾病相关时,新冠肺炎感染不断改变我们对其临床过程的理解。客观的介绍一例非特异性溃疡性结肠炎(NUC)和新冠肺炎感染患者的临床病例。材料和方法:医学文献、一般临床、实验室和仪器数据,以及结肠镜检查中获得的苏木精和伊红染色的生物状态的组织学检查。后果本文介绍了一例患者的病史,该患者表现为与亚临床形式的新冠肺炎感染相关的严重全NUC,前者是伴随病理的死亡原因。结论。该临床病例描述了NUC不良结果的变体,其表现的原因之一是非典型形式的新冠肺炎感染,这成为肠道自身免疫炎症过程的触发因素。对这两种病理的发病机制和表现的新知识的积累将有可能提高治疗的有效性,并预测联合病理的过程和结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
NON-SPECIFIC ULCERATIVE COLITIS AND COVID-19, A CASE STUDY
Background. COVID-19 infection keeps changing our understanding of its clinical course when associated with various somatic diseases. Objective. To present a clinical case of a patient with non-specific ulcerative colitis (NUC) and COVID-19 infection. Material and methods: medical documentation, general clinical, laboratory and instrumental data as well as histological examination of bioptates stained with hematoxylin and eosin that were obtained during colonoscopy. Results. The article presents a case history of a patient with manifestations of severe total NUC developed in association with the subclinical form of COVID-19 infection, the former being the cause of death in concomitant pathology. Conclusions. This clinical case describes a variant of an unfavorable outcome of NUC, one of the reasons for the manifestation of which was the atypical form of COVID-19 infection, which became a trigger for an autoimmune inflammatory process in the intestine. The accumulation of new knowledge about the features of the pathogenesis and manifestations of both pathologies will make it possible to improve the effectiveness of treatment and predict the course and outcomes of combined pathology.
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